- Application of isotope-enriched 3-amino-1-propanesulfonic acid and derivative thereof
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The present invention relates to the use of isotopically enriched compounds of general formula I or pharmaceutically acceptable salts or esters thereof, and corresponding pharmaceutical compositions for the prevention and treatment of cerebrovascular diseases and disorders, such as vascular dementia, cerebral apoplexy, and the like. In the formula (I), R1R2X-CR2-CH2-CH2-SO3H is shown in the specification.
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Paragraph 0212; 0215
(2021/05/15)
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- METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID
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The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.
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Page/Page column 42
(2008/12/06)
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