- INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE
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Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
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Paragraph 0404
(2021/09/04)
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- ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES
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The present invention is to provide a molecule suitable for use in an optoelectronic device. To this end, an organic molecule for an optoelectronic device of the present invention comprises a structure of chemical formula I. In the chemical formula I: T, V, and W are selected from the group consisting of R^A, R^1, and A; X and Y are selected from the group consisting of R^1 and A; and A is selected from the group consisting of CN and CF_3.COPYRIGHT KIPO 2020
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Paragraph 0557-0558
(2020/05/23)
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- ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE
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An organic electroluminescence device includes a first electrode, a hole transport region disposed on the first electrode, an emission layer disposed on the hole transport region, an electron transport region disposed on the emission layer, and a second electrode disposed on the electron transport region, wherein the emission layer includes a polycyclic compound containing two electron donors and one electron acceptor, and the electron acceptor includes a benzonitrile part and a pyridine part, thereby showing high emission efficiency.
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Paragraph 0117; 0118
(2019/10/12)
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- HEPATITIS B CORE PROTEIN MODULATORS
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The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:
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Page/Page column 113; 114
(2018/04/13)
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- HETEROCYCLIC COMPOUND AND USE THEREOF
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The present invention provides a heterocycle derivative having a superior amyloid β production inhibitory activity and/or a superior γ-secretase modulation activity, and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a salt thereof.
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Page/Page column 71
(2012/03/26)
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- BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF
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Compounds of structural formula I: are GPR119 agonists and are useful for the treatment, control or prevention of disorders responsive to agonism of GPR119, such as metabolic-related disorders such as type I diabetes, type II diabetes, inadequate glucose tolerance, insulin resistance, hyperglycemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, dyslipidemia or syndrome X. The compounds are also reported as being useful for controlling weight gain, controlling food intake, and inducing satiety in mammals.
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Page/Page column 53-54
(2012/01/06)
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- Certain pyrazoline derivatives with kinase inhibitory activity
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The present invention provides certain pyrazoline compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions and methods of using the compositions in the treatment of various diseases.
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Page/Page column 104-105
(2008/12/06)
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