- AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE
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Relating to a compound represented by formula (I) and a pharmaceutically acceptable salt of the compound, and an application of the compound as an S1P1 agonist.
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Paragraph 0185-0186
(2021/10/15)
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- Preparation method 5- hydroxyl -7- azaindole (by machine translation)
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The invention discloses 5 -hydroxy- 7 7-azaindole preparation method, which takes 5 - X - 2 -nitropyridine as a raw material to react with benzyl alcohol sodium or sodium alkyl sodium alkoxide to generate 5 - R - 2 -nitropyridine, which is benzyl, methyl or ethyl X after being closed by a Grignard reagent ring after cyclization is carried, out, and ;R is high, yield. (by machine translation)
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- PYRROLO [2,3-B] PYRIDINES AS KINASE MODULATORS
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Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
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Page/Page column 66
(2008/12/07)
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