- A green chemistry approach to ibuprofen piconol
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Ibuprofen piconol synthesis has been described. The use of solid catalyst has demonstrated green chemistry approach with promoted atom economy of 94% compared to the reported 68%.
- Raju, C. M. Haricharan,Lakshmi, P. Naga,Srinivas,Reddy,Acharyulu, Palle V. R.
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- METHOD FOR PRODUCING ESTER GROUP-CONTAINING COMPOUND
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The present invention provides a novel method for producing an ester group-containing compound and a derivative produced using the compound as a synthetic intermediate. The invention also provides a polymerizable composition containing the compound obtained by the production method and a film-shaped polymer obtained by polymerizing the polymerizable composition. The present invention is a method for producing an ester group-containing compound, the method including a mixing step of mixing a condensing agent, a Bronsted acid, a carboxylic acid, and a phenol or an alcohol to prepare a reaction mixture. The Bronsted acid selected is other than the condensing agent, the carboxylic acid, and the phenol.
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Paragraph 0157-0162
(2019/03/08)
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- Method for producing ester group-containing compound being useful for optical material applications such as optical compensation films
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The present invention provides a novel method for producing an ester group-containing compound and a derivative produced by using the compound as a synthetic intermediate. The present invention also provides a polymerizable composition containing the compound obtained by the production method and a film-shaped polymer obtained by polymerizing the polymerizable composition. The present invention is a method for producing an ester group-containing compound, the method including a mixing step of mixing a condensing agent, a Bronsted acid, carboxylic acid, and phenol or alcohol to prepare a reaction mixture. The Bronsted acid is selected from anything other than the condensing agent, the carboxylic acid, and the phenol.
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Paragraph 0215-0218
(2019/07/16)
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- ZINC COMPLEX
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A zinc complex characterized in exhibiting an octahedral structure and being configured from repeating units represented by general formula (I): wherein L represents a linker region, and R1 represents a C1-4 alkyl group, which can have a halogen atom.
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Paragraph 0200
(2016/05/19)
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- Alterntnate routes for the synthesis of ibuprofen piconol
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New, improved and alternate methods for the synthesis of ibuprofen piconol from ibuprofen and pyridine-2-methanol have been demonstrated with different carboxyl activating groups.
- Haricharan Raju,Anand, C. Vijay,Dubey,Acharyulu, Palle V. R.
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p. 170 - 172
(2008/02/09)
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- Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propionic acids and use
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The present invention relates to phenylacetic acid ester derivatives of the following general formula: STR1 wherein, R is selected from the group consisting of lower alkyl (other than ethyl) and substituted lower alkyl, and R' may be a hydrogen or methyl.
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