cas 1147-23-5, 5-Iodocytidine | Articles data

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A DNA-inspired synthetic ion channel based on G-C base pairing
A dinucleoside containing guanosine and cytidine at the end groups has been prepared using a modular one-pot azide-alkyne cycloaddition. Single channel analysis showed that this dinucleoside predominantly forms large channels with 2.9 nS conductance for the transport of potassium ions across a phospholipid bilayer. Transmission electron microscopy, atomic force microscopy, and circular dichroism spectroscopy studies reveal that this dinucleoside can spontaneously associate through Watson-Crick canonical H-bonding and π-π stacking to form stable supramolecular nanostructures. Most importantly, the ion channel activity of this G-C dinucleoside can be inhibited using the nucleobase cytosine.
Das, Rabindra Nath,Kumar, Y. Pavan,Schütte, Ole Mathis,Steinem, Claudia,Dash, Jyotirmayee
p. 34 - 37
(2015)
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Effective Synthesis of 5-Iodo Derivatives of Pyrimidine Morpholino Nucleosides
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Vohtancev, Ivan P.,Sherstyuk, Yuliya V.,Silnikov, Vladimir N.,Abramova, Tatyana V.
p. 332 - 342
(2018/05/29)

Preparation method of novel nucleoside derivatives
The invention aims at providing a synthetic method of fluorescent nucleoside derivatives obtained by a reaction with 4-substituted phenylacetylene and 5-iodocytidine as raw materials in the catalysis of palladium dichloride/CuI. The method is characterize
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Paragraph 0015-0016; 0019-0020

(2017/08/29)

ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
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Page/Page column 634; 635

(2016/06/15)

ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
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Page/Page column 642

(2016/06/28)

Alternative nucleic acid molecules and uses thereof
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
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Paragraph 2219; 2220

(2015/11/09)

Highly efficient method for C-5 halogenation of pyrimidine-based nucleosides in ionic liquids
A novel, highly efficient, convenient, and benign methodology for C-5 halogenation of pyrimidine-based nucleosides has been developed using N-halosuccinimides as halogenating reagents without using any catalyst in ionic liquid medium. The ionic liquids were successfully recovered and reused for all the reactions. Georg Thieme Verlag Stuttgart.
Kumar, Vineet,Yap, Jeremy,Muroyama, Andrew,Malhotra, Sanjay V.
experimental part
p. 3957 - 3962
(2010/03/26)

Microwave-assisted C-5 iodination of substituted pyrimidinones and pyrimidine nucleosides
Direct microwave-assisted iodination of several pyrimidinones and pyrimidine nucleosides with N-iodosuccinimide to give the corresponding 5-iodo derivatives is described. Application of this reaction to polymer-bound pyrimidinones was also investigated.
Paolini, Lisa,Petricci, Elena,Corelli, Federico,Botta, Maurizio
p. 1039 - 1042
(2007/10/03)

The synthesis of 5-iodocytidine phosphoramidite for heavy atom derivatization of RNA
The synthesis of an RNA phosphoramidite of 5-iodocytidine is reported. This heavy atom cytidine derivative was incorporated into four RNAs. Oligoribonucleotides with 5-iodocytidine will be useful for solving the X-ray crystallographic phase problem and for photochemical cross-linking studies.
Irani, Rostem J.,SantaLucia Jr., John
p. 8961 - 8964
(2007/10/03)

Synthesis and Physicochemical Properties of 6-O-Cyclopyrimidine Nucleosides
Cyclization of 5-iodo-1-(β-D-xylofuranosyl)uracil and -cytosine with sodium methoxide afforded 6,3'-O-cyclouridine (IIa) and -cytidine (IIc), respectively.The rate of cyclization of 5-iodopyrimidine nucleosides is greatly dependent on the ring size formed
Maruyama, Tokumi,Sato, Sumiko,Honjo, Mikio
p. 2688 - 2697
(2007/10/02)

Chemical Properties

Boiling Point: 565.461 °C at 760 mmHg
Flash Point:295.78 °C
Density: 2.527 g/cm³
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Storage Temp.:-20°C
Vapor Pressure: 3.85E-15mmHg at 25°C
Refractive Index: 1.85
PKA: 13.48±0.70(Predicted)
Sensitive: Light Sensitive
PSA: 130.83000
LogP: -1.37720

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1147-23-5

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Chemical Properties

Boiling Point: 565.461 °C at 760 mmHg

Flash Point:295.78 °C

Density: 2.527 g/cm³

Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Storage Temp.:-20°C

Vapor Pressure: 3.85E-15mmHg at 25°C

Refractive Index: 1.85

PKA: 13.48±0.70(Predicted)

Sensitive: Light Sensitive

PSA: 130.83000

LogP: -1.37720

Global suppliers and manufacturers of 1147-23-5total 61 suppliers on LookChem

Article Database

1147-23-5

Articles about 1147-23-5Total 10 be found

More Articles about upstream products of 1147-23-5

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Chemical Properties

Boiling Point: 565.461 °C at 760 mmHg

Flash Point:295.78 °C

Density: 2.527 g/cm3

Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Storage Temp.:-20°C

Vapor Pressure: 3.85E-15mmHg at 25°C

Refractive Index: 1.85

PKA: 13.48±0.70(Predicted)

Sensitive: Light Sensitive

PSA: 130.83000

LogP: -1.37720

Global suppliers and manufacturers of 1147-23-5total 61 suppliers on LookChem

Density: 2.527 g/cm³