A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set of fluorinated 1-desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines bearing a sugar-mimicking group is proposed. Georg Thieme Verlag Stuttgart.
Iaroshenko, Viktor O.,Sevenard, Dmitri V.,Volochnyuk, Dmitriy M.,Wang, Yan,Martiloga, Alexander,Tolmachev, Andrei O.
scheme or table
p. 1865 - 1875
(2009/12/30)
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