Analogs of the β-turn of the cyclodepsipeptide didemnin B
Three side chain analogs of didemnin B were synthesized. All three analogs of the only conventional type II β-turn present in didemnin B differed in the functionality incorporated in the threonine residue. The cytotoxic activities of these analogs were evaluated, and one of them exhibited weak activity.
Ramanjulu, Joshi M.,Joullie, Madeleine M.
p. 311 - 314
(2007/10/02)
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