- Synthesis of chalcones bearing 2-hydroperoxy-3-methyl-3-butenyl or 2-hydroxy-3-methyl-3-butenyl group from prenylated chalcones
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Chalcones bearing 2-hydroperoxy-3-methyl-3-butenyl or 2-hydroxy-3-methyl-3-butenyl groups, such as xanthoangelol E (1a), xanthoangelol D (2a), psorachalcone A (2 b), xanthohumol D (2c), and related derivatives were first synthesized by using the ene react
- Sugamoto, Kazuhiro,Yoshifuji, Toru,Soejima, Shuhei,Honda, Yoshihiro
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supporting information
p. 1523 - 1527
(2020/04/01)
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- Synthesis method and uses of natural product Xanthohumol D and analogue thereof
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The invention discloses a synthesis method and uses of a natural product Xanthohumol D (I) and an analogue (II) thereof, wherein the structural formula is defined the specification, the novel isopentenyl chalcone compound is obtained, and Xanthohumol D has good inhibitory activity on bacillus subtilis. According to the invention, the preparation method has advantages of few process steps and easily available raw materials, and is suitable for industrial production.
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