cas 469-62-5, PROPOXYPHENE | Articles data

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Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence
A pharmaceutical composition for the treatment of an increased urge to urinate or urinary incontinence, comprising an effective amount of at least a compound selected from the group consisting of codeine, dihydrocodeine, dextropropoxyphene, meptazinol and tilidine. Also disclosed are methods of treatment using the pharmaceutical compositions and preferred dosages for the treatment methods.
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(2008/06/13)

Synthesis and purification of d-propoxyphene hydrochloride
New and improved synthesis of α-d-propoxyphene hydrochloride by acid chloride reaction between propionyl chloride and α-d-1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol (d-oxyphene) with small amounts of thionyl chloride improves yield and substantially simplifies purification.
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(2008/06/13)

Polypeptide propoxyphene derivatives for immunoassay reagents
Novel compounds are provided which are derivatives of 1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol. The indicated alcohol is employed to prepare the monoester of a dibasic acid which is conjugated with an antigen for the production of antibodies which recognize both propoxyphene and its N-desmethyl metabolite in immunoassays.
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(2008/06/13)