Nickel-mediated inter- and intramolecular reductive cross-coupling of unactivated alkyl bromides and aryl iodides at room temperature
A nickel-mediated intermolecular reductive cross-coupling reaction of unactivated alkyl bromides and aryl iodides at room temperature has been developed and successfully extended to less explored intramolecular versions and tandem cyclization-intermolecular cross-coupling. Highly stereoselective (or stereospecific) synthesis of linear-fused perhydrofuro[2,3-b]furan (pyran) and spiroketal skeletons allows rapid access to these useful building blocks, which would be potentially valuable in the synthesis of relevant natural products. A rational explanation for the formation of contiguous stereogenic centers is given. Copyright
Yan, Chang-Song,Peng, Yu,Xu, Xiao-Bo,Wang, Ya-Wen
p. 6039 - 6048
(2012/06/18)
INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES
Disclosure is provided for carbamate compounds that prevent, remove and/or inhibit the formation of biofilms, compositions including these compounds, devices including these compounds, and methods of using the same.
-
Page/Page column 33
(2012/02/01)
SMALL MOLECULE MODIFIERS OF MICRORNA MIR-122
MicroRNAs are a class of endogenous regulators of gene function. Aberrant regulation of microRNAs has been linked to various human diseases, most importantly cancer. Small molecule intervention of microRNA misregulation has the potential to provide new th
-
Page/Page column 38; 41
(2011/08/08)
Small molecule modifiers of MicroRNA miR-122 function for the treatment of hepatitis C Virus infection and hepatocellular carcinoma
MicroRNAs are a recently discovered new class of important endogenous regulators of gene function. Aberrant regulation of microRNAs has been linked to various human diseases, most importantly cancer. Small molecule intervention of microRNA misregulation h
Young, Douglas D.,Connelly, Colleen M.,Grohmann, Christoph,Deiters, Alexander
supporting information; experimental part
p. 7976 - 7981
(2010/08/05)
A facile one-pot synthesis of N-substituted tetrahydroquinolines
An uncatalyzed one-pot synthesis of N-substituted tetrahydroquinolines was achieved in good yields by the reaction of quinoline and alkyl/acyl halides with Hantzsch dihydropyridine ester under mild reaction conditions.
Babu, Thelagathoti Hari,Shanthi, Gnanamani,Perumal, Paramasivan T.
experimental part
p. 2881 - 2884
(2009/09/06)
Depressant 1,2-dihydroquinolines and related derivatives.
-
Muren,Weissman
p. 49 - 53
(2007/10/07)
More Articles about upstream products of 54915-68-3