- Method for synthesizing succinic acid compounds
-
The invention provides a method for synthesizing succinic acid compounds. The method specifically comprises the following steps: adding a substrate, a photocatalyst and an alkali into a reaction tube,adding a reducing agent and a solvent under the atmosphere of CO2, conducting reacting under the irradiation of visible light, carrying out quenching treatment after the raw materials react completely, and then conducting separating and purifying to obtain a dicarboxylated product of olefin, namely a succinic acid compound. The photocatalyst is 4CzIPN or Ir[(ppy)2(dtbppy)]PF6 and the like, and the reaction substrate comprises 1,1-diaryl ethylene, a monoaryl substituted olefin compound, an acrylate compound and allene. According to the scheme provided by the invention, the reaction conditionsare mild, the applicability of the reaction substrate is wide, and the yield is basically not influenced under the condition that the reaction substrate is amplified to the gram scale; and meanwhile,the invention overcomes the defects of high toxicity of reagents and harsh reaction conditions in the prior art, and has a good industrial application prospect.
- -
-
Paragraph 0028-0036; 0040
(2019/08/01)
-
- Direct β-Selective Hydrocarboxylation of Styrenes with CO2 Enabled by Continuous Flow Photoredox Catalysis
-
The direct β-selective hydrocarboxylation of styrenes under atmospheric pressure of CO2 has been developed using photoredox catalysis in continuous flow. The scope of this methodology was demonstrated with a range of functionalized terminal styrenes, as well as α-substituted and β-substituted styrenes.
- Seo, Hyowon,Liu, Aofei,Jamison, Timothy F.
-
supporting information
p. 13969 - 13972
(2017/10/17)
-
- Enamines; 45. A New Simple Synthesis of 2-Phenylsuccinic Acids
-
A simple route to 2-phenylsuccinic acids consists of the reaction of 1,1-dimorpholinoethene with β-nitrostyrenes at room temperature and hydrolysis of the 1:1 adduct thus obtained with hydrochloric acid.The method affords good overall yields of 2-phenylsuccinic acids.
- Rossi, Elisabetta,Sassano, Silvia,Stradi, Riccardo
-
p. 765 - 766
(2007/10/02)
-