Microwave-assisted ring opening of epoxides: A general route to the synthesis of 1-aminopropan-2-ols with anti malaria parasite activities
A series of 1-aminopropan-2-ols were synthesized and evaluated against two strains of malaria, Plasmodium falciparum FCR3 (chloroquine-resistant) and 3D7 (chloroquine-sensitive). Microwave-assisted ring opening of epoxides (aryl and alkyl glycidyl ethers,
Robin, Aélig,Brown, Fraser,Bahamontes-Rosa, Noemí,Wu, Binghua,Beitz, Eric,Kun, Jürgen F. J.,Flitsch, Sabine L.