117666-96-3

Basic information

• Product Name: FMOC-BPA-OH
• Synonyms: N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-4-BENZOYL-L-PHENYLALANINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-4-BENZOYL-L-PHENYLALANINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-P-BENZOYL-L-PHENYLALANINE;N-ALPHA-FMOC-4-BENZOYL-L-PHENYLALANINE;FMOC-P-BENZOYLPHENYLALANINE;FMOC-P-BZ-PHENYLALANINE;FMOC-P-BZ-PHE-OH;FMOC-PHE(P-BZ)-OH
• CAS NO: 117666-96-3
• Molecular Formula: C31H25NO5
• Molecular Weight: 491.53
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 117666-96-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 729.037 °C at 760 mmHg
• Flash Point: 394.708 °C
• Appearance: White/Powder
• Density: 1.288 g/cm³
• Vapor Pressure: 2.61E-22mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: 2-8°C
• PKA: 3.68±0.10(Predicted)
• BRN: 7672022
• CAS DataBase Reference: FMOC-BPA-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-BPA-OH(117666-96-3)
• EPA Substance Registry System: FMOC-BPA-OH(117666-96-3)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 117666-96-3(Hazardous Substances Data)

Usage

Description

FMOC-BPA-OH, also known as 9-fluorenylmethoxycarbonyl-3,5-bis(phenyl)-4-aminophenol, is a synthetic reagent with a white to off-white powder appearance. It is widely utilized in the field of organic chemistry and pharmaceutical research due to its unique chemical properties.

Uses

Used in Pharmaceutical Research:
FMOC-BPA-OH is used as a reagent for the identification of potent muscarinic acetylcholine receptor antagonists. These antagonists play a crucial role in the treatment of various neurological and psychiatric disorders, such as Alzheimer's disease, schizophrenia, and chronic obstructive pulmonary disease (COPD). The compound aids in the development of new drugs targeting these receptors, potentially leading to more effective treatments for these conditions.
Used in Organic Chemistry:
In the field of organic chemistry, FMOC-BPA-OH serves as a valuable reagent for the synthesis of various organic compounds. Its unique chemical structure allows for the formation of new bonds and the modification of existing ones, facilitating the creation of novel molecules with potential applications in various industries.
Used in Chemical Synthesis:
FMOC-BPA-OH is also employed in chemical synthesis as a protecting group for amino groups. This function is essential in the synthesis of peptides, proteins, and other biomolecules, as it prevents unwanted side reactions and ensures the selective protection of specific functional groups. The use of FMOC-BPA-OH in this capacity contributes to the development of more efficient and accurate synthetic methods for the production of complex molecules.

InChI:InChI=1/C31H25NO5/c33-29(21-8-2-1-3-9-21)22-16-14-20(15-17-22)18-28(30(34)35)32-31(36)37-19-27-25-12-6-4-10-23(25)24-11-5-7-13-26(24)27/h1-17,27-28H,18-19H2,(H,32,36)(H,34,35)/t28-/m0/s1