13081-32-8

Basic information

• Product Name: H-D-LEU-OTBU HCL
• Synonyms: H-D-LEU-OTBU HCL;H-D-LEU-OBUT HCL;D-LEUCINE T-BUTYL ESTER HYDROCHLORIDE SALT;D-LEUCINE T-BUTYL ESTER HYDROCHLORIDE;D-LEUCINE-OTBU HCL;D-Leucine, 1,1-diMethylethyl ester, hydrochloride;(R)-2-Amino-4-methylpentanoic acid tert-butyl ester hydrochloride salt;D-Leucine T-butyl ester. HCL
• CAS NO: 13081-32-8
• Molecular Formula: C10H22ClNO2
• Molecular Weight: 223.74
• Product Categories: Amino Acid tert-Butyl Esters;Amino Acids;Amino Acids (C-Protected);Biochemistry
• Mol File: 13081-32-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Refractive Index: -19 ° (C=2, EtOH)
• Storage Temp.: -15°C
• CAS DataBase Reference: H-D-LEU-OTBU HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-LEU-OTBU HCL(13081-32-8)
• EPA Substance Registry System: H-D-LEU-OTBU HCL(13081-32-8)

Safety Data

• Hazardous Substances Data: 13081-32-8(Hazardous Substances Data)

Usage

Description

H-D-LEU-OTBU HCL, also known as D-Leucine tert-butyl ester hydrochloride, is a protected form of D-Leucine, an unnatural isomer of L-Leucine. It is a crystalline compound with various applications in different industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
H-D-LEU-OTBU HCL is used as a pharmaceutical compound for its analgesic effects in humans. It serves as a potential candidate for pain management and relief, offering an alternative to traditional pain medications.
Used in Bacterial Cell Cultures:
In the field of microbiology, H-D-LEU-OTBU HCL is used as an auto-inhibitor of lactic streptococci in culture. Its inhibitory activity helps control bacterial growth and can be utilized in studying bacterial behavior and developing targeted treatments.
Used in Chemical Synthesis:
H-D-LEU-OTBU HCL, being a protected form of D-Leucine, is used as an intermediate in the synthesis of various chemical compounds. Its crystalline nature makes it suitable for use in chemical reactions, contributing to the development of new drugs and materials.

Downstream Products

• 27167-65-3 (S)-tert-butyl 2-((S)-2-(((benzyloxy)carbonyl)amino)propanamido)-4-methylpentanoate 
• 149207-52-3 FMOC-L-Tyr-Gly-Gly-L-Phe-L-Leu-OH 
• 57700-01-3 Boc-AzaPhe-Leu-OMe 
• 1429433-32-8 Boc-AzaPhe-Leu-OH 
• 1429433-54-4 H-AzaPhe-Leu-OH hydrochloride 
• 1476068-51-5 tert-butyl N-{[1-(4-bromo-2-isopropylphenyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}-L-leucinate 
• 1462366-49-9 (S)-4-methyl-2-{methyl[methyl(phenyl)carbamoyl]amino}pentanoic acid 
• 201605-91-6 5-isobutyl-1,3-dimethyl-5-phenylimidazolidine-2,4-dione 
• 21282-11-1 pyroGlu-Leu 
• 1337556-02-1 (S)-2-{(2S,3S,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid 
• 1337556-54-3 C₄₂H₆₆N₆O₉ 
• 1337555-97-1 (S)-2-{(2R,3S,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid 
• 1337556-47-4 C₄₂H₆₆N₆O₉ 
• 1197285-78-1 (S)-2-{(2R,3R,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid 

Relevant articles and documents

N-cyclopentyl modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: (wherein R1, R3, R4, R5, R6, R7, R8, X, n, x and y are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.