147688-40-2

Basic information

• Product Name: FMOC-TYR(2-BR-Z)-OH
• Synonyms: N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-2-BROMOCARBOBENZOXY-L-TYROSINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-(2-BROMOBENZYLOXYCARBONYL)-L-TYROSINE;N-ALPHA-FMOC-O-2-BROMOBENZYLOXYCARBONYL-L-TYROSINE;N-ALPHA-FMOC-O-2-BROMO-CBZ-L-TYROSINE;FMOC-O-(2-BROMOBENZYLOXYCARBONYL)-L-TYROSINE;FMOC-O-2-BROMO-Z-L-TYROSINE;FMOC-L-TYR(2-BR-Z)-OH;FMOC-TYR(2-BROMO-Z)-OH
• CAS NO: 147688-40-2
• Molecular Formula: C32H26BrNO7
• Molecular Weight: 616.46
• Product Categories: Amino Acids
• Mol File: 147688-40-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 791.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.452±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.89±0.10(Predicted)
• CAS DataBase Reference: FMOC-TYR(2-BR-Z)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-TYR(2-BR-Z)-OH(147688-40-2)
• EPA Substance Registry System: FMOC-TYR(2-BR-Z)-OH(147688-40-2)

Safety Data

• Hazardous Substances Data: 147688-40-2(Hazardous Substances Data)

Usage

Description

FMOC-TYR(2-BR-Z)-OH, also known as N-(9-fluorenylmethoxycarbonyl)-L-tyrosine (2-bromo-benzyloxycarbonyl), is a synthetic compound commonly utilized in the field of organic chemistry and peptide synthesis. It is a protected amino acid derivative that plays a crucial role in the development of various peptide-based compounds and pharmaceuticals. The presence of the 9-fluorenylmethoxycarbonyl (Fmoc) group and the 2-bromo-benzyloxycarbonyl (2-Br-Z) group provides protection to the amino acid, allowing for selective deprotection and coupling reactions during peptide synthesis.

Uses

Used in Pharmaceutical Industry:
FMOC-TYR(2-BR-Z)-OH is used as an intermediate for the synthesis of dipeptide mimic combinatorial libraries through successive amide alkylations. This application is essential for the development of new drugs and therapeutic agents, as it enables the creation of a diverse range of peptide-based compounds with potential biological activities.
Used in Research and Development:
In the field of research and development, FMOC-TYR(2-BR-Z)-OH serves as a valuable tool for the synthesis of novel peptides and peptidomimetics. Its use in the preparation of dipeptide mimic combinatorial libraries allows researchers to explore the structure-activity relationships of various peptide sequences, leading to the discovery of new bioactive molecules with potential applications in medicine and biotechnology.
Used in Chemical Synthesis:
FMOC-TYR(2-BR-Z)-OH is also employed in chemical synthesis, particularly in the preparation of complex organic molecules and natural products. Its unique structural features, including the Fmoc and 2-Br-Z protecting groups, make it an attractive building block for the synthesis of various target molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.