163959-79-3

Basic information

• Product Name: 1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI)
• Synonyms: 1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI);(R)-(+)-2-(a-methylmethanamine)-1H-benzimidazole, min. 98% (R)-Me-BIMAH;(R)-(+)-2-(alpha-methylmethanamine)-1H-benzimidazole, min. 98% (R)-Me-BIMAH;(R)-(+)-2-(α-MethylMethanaMine)-1H-benziMidazole, Min. 98% (R)-Me-BIMAH;(1R)-1-(1H-1,3-benzodiazol-2-yl)ethan-1-amine;(R)-(+)-2-(α-methylmethanamine)-1H-benzimidazole;(1R)-1-(1H-benzimidazol-2-yl)ethanamine;-methylmethanamine)-1H-benzimidazole, min. 98% (R)-Me-BIMAH
• CAS NO: 163959-79-3
• Molecular Formula: C9H11N3
• Molecular Weight: 161.2
• Product Categories: BENZIMIDAZOLE;organic amine
• Mol File: 163959-79-3.mol
• Article Data: 11

Chemical Properties

• Melting Point: 188-190°C
• Appearance: white to off-white/solid
• Sensitive: air sensitive
• CAS DataBase Reference: 1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI)(163959-79-3)
• EPA Substance Registry System: 1H-Benzimidazole-2-methanamine,alpha-methyl-,(R)-(9CI)(163959-79-3)

Safety Data

• Hazardous Substances Data: 163959-79-3(Hazardous Substances Data)

Usage

Reaction

Efficient ruthenium catalyst for asymmetric hydrogenation of aryl ketones.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 302-72-7 rac-Ala-OH 
• 56-41-7 L-alanin 
• 73042-50-9 1-(benzimidazol-2-yl)ethylamine 
• 141-78-6 ethyl acetate 
• 338-69-2 D-Alanine 
• 7324-05-2 L-alanine amide 
• 25810-63-3 1-(1H-benzimidazol-2-yl)-ethylamine; dihydrochloride 
• 25810-58-6 (D,L)-2-(1-benzoylaminoethyl)benzimidazole 

Downstream Products

• 135875-07-9 (S)-3-Methyl-2,3-dihydro-1H-benzo[d]imidazo[1,5-a]imidazole 
• 135875-08-0 (S)-1-Methyl-1,2,3,4-tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazine 

Relevant articles and documents

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Asymmetric Hydrogenation of 3,5-Bistrifluoromethyl Acetophenone in Pilot Scale with Industrially Viable Ru/Diphosphine-Benzimidazole Complexes

A novel efficient asymmetric hydrogenation (AH) process was developed for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethanol (3), using a catalyst Ru/(4R,5R)-(+)-4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxoane-(R,R-Diop)-2R-(α-met

Stereoselective chemoenzymatic synthesis of enantiopure 1-(Heteroaryl)ethanamines by lipase-Catalysed kinetic resolutions

The efficient chemical synthesis and enzymatic kinetic resolution of a family of 1-(heteroaryl)ethanamines have been performed with lipases responsible for the preparation of nitrogenated compounds in high optical purity. Thus, Candida antarctica lipase type B has been identified as an excellent biocatalyst for the stereoselective production of the corresponding enantiomerically enriched (B)-acetamides and (S)-amines. A similar effect of the heteroatom in the cyclic ring has been observed in terms of reactivity and enantio- selectivity, with benzoxazole, benzothiazole and benzimidazole derivatives being obtained with excellent enantiopurities after one day of reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009.