252049-06-2 Usage
General Description
FMOC-N-ME-THR-OH is a chemical compound that belongs to the class of amino acids and derivatives. It is a derivative of threonine, an essential amino acid that plays a crucial role in protein synthesis and various metabolic processes in the body. FMOC-N-ME-THR-OH is often used in organic chemistry and biochemistry research as a building block for the synthesis of peptides and proteins. Its FMOC (fluorenylmethyloxycarbonyl) group serves as a protecting group for the threonine amino acid, allowing for selective modification and manipulation of the amino acid in the synthesis of complex molecules. Overall, FMOC-N-ME-THR-OH is an important chemical compound in the field of chemical and biological research, serving as a key component in the development of various peptide-based drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 252049-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,2,0,4 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 252049-06:
(8*2)+(7*5)+(6*2)+(5*0)+(4*4)+(3*9)+(2*0)+(1*6)=112
112 % 10 = 2
So 252049-06-2 is a valid CAS Registry Number.
252049-06-2Relevant articles and documents
An improved synthesis of Fmoc-N-methyl serine and threonine
Bahekar, Rajesh H.,Jadav, Pradip A.,Patel, Dipam N.,Prajapati, Vijay M.,Gupta, Arun A.,Jain, Mukul R.,Patel, Pankaj R.
, p. 5003 - 5005 (2007)
An improved method for the synthesis of Fmoc-N-methyl serine and threonine has been developed, which involves formation and subsequent reduction of the corresponding oxazolidinone with a Lewis acid under mild conditions, with improved yields and shorter reaction times.
Solid-Phase Total Synthesis of the Proposed Structure of Coibamide A and Its Derivative: Highly Methylated Cyclic Depsipeptides
Sable, Ganesh A.,Park, Jaekwan,Kim, Hyunsik,Lim, Soo-Jeong,Jang, Soonmin,Lim, Dongyeol
, p. 7043 - 7052 (2015/11/16)
The solid-phase total synthesis of the proposed structure of cyclic depsipeptide coibamide A and its derivative O-desmethyl coibamide A is reported. In this study, we demonstrate the solid-phase synthetic strategy and final solution-phase O-methylation fo