316149-01-6

Basic information

• Product Name: IMpurity of Etoricoxib
• Synonyms: IMpurity of Etoricoxib;Etoricoxib Impurity 10;Etoricoxib Impurity 9;Etoricoxib Sulfoxide;Etoricoxib Impurity B
• CAS NO: 316149-01-6
• Molecular Formula: C₁₈H₁₅ClN₂OS
• Molecular Weight: 342.8425
• Mol File: 316149-01-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 122-123 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3); ethyl acetate (141-78-6))
• Boiling Point: 489.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3(Predicted)
• PKA: 3.75±0.12(Predicted)
• CAS DataBase Reference: IMpurity of Etoricoxib(CAS DataBase Reference)
• NIST Chemistry Reference: IMpurity of Etoricoxib(316149-01-6)
• EPA Substance Registry System: IMpurity of Etoricoxib(316149-01-6)

Safety Data

• Hazardous Substances Data: 316149-01-6(Hazardous Substances Data)

Usage

Description

IMpurity of Etoricoxib is a compound that is associated with Etoricoxib, a selective COX-2 inhibitor used for the treatment of various pain and inflammation conditions. It is an impurity that may be present during the manufacturing process or formulation of Etoricoxib.
Used in Pharmaceutical Industry:
IMpurity of Etoricoxib is used as a reference material for quality control and assurance in the pharmaceutical industry. It helps in the development and validation of analytical methods, ensuring the purity and safety of the final drug product.
Used in Research and Development:
IMpurity of Etoricoxib is used as a research tool for studying the effects of impurities on the efficacy, safety, and stability of Etoricoxib. This helps in understanding the potential risks and side effects associated with the drug and contributes to the overall drug development process.
Used in Regulatory Compliance:
IMpurity of Etoricoxib is used for regulatory compliance purposes, as it is essential to demonstrate the quality and safety of the drug product to regulatory authorities. The presence of impurities in a drug can affect its performance and safety profile, so it is crucial to monitor and control these impurities during the drug development and manufacturing process.
Used in Drug Safety Assessment:
IMpurity of Etoricoxib is used in drug safety assessment to evaluate the potential toxicological effects of the impurity. This information is vital for setting acceptable limits for impurities in the final drug product and ensuring patient safety.
Used in Drug Metabolism Studies:
IMpurity of Etoricoxib is used in drug metabolism studies to understand how the impurity is metabolized in the body and its potential impact on the drug's pharmacokinetics and pharmacodynamics. This information can help in optimizing the drug's dosage and administration, as well as identifying potential drug-drug interactions.

Downstream Products

• 866336-08-5 thiobutyric acid S-[4-(5-chloro-6'-methyl-[2,3']bipyridinyl-3-yl)phenyl] ester