31954-27-5

Basic information

• Product Name: BOC-GLY-OME
• Synonyms: N-[(1,1-Dimethylethoxy)carbonyl]glycine Methyl Ester;N-(tert-Butoxycarbonyl)glycine Methyl ester, 97%+;N-(tert-Butoxycarbonyl)glycine methyl ester 97%;N-(tert-Butoxycarbonyl)glycine Methyl Ester;Boc-glycine methyl ester≥ 98% (GC);N-BOC-Glycine methyleester;METHYL 2-[(TERT-BUTOXYCARBONYL)AMINO]ACETATE;BOC-GLY-OME
• CAS NO: 31954-27-5
• Molecular Formula: C₈H₁₅NO₄
• Molecular Weight: 189.21
• Product Categories: Amino Acid Derivatives;Glycine;Peptide Synthesis;Miscellaneous
• Mol File: 31954-27-5.mol
• Article Data: 61

Chemical Properties

• Boiling Point: 190 °C(lit.)
• Flash Point: 109 °C
• Appearance: /
• Density: 1.28 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00845mmHg at 25°C
• Refractive Index: n20/D 1.437(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform, Ethyl Acetate
• PKA: 11.06±0.46(Predicted)
• CAS DataBase Reference: BOC-GLY-OME(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-GLY-OME(31954-27-5)
• EPA Substance Registry System: BOC-GLY-OME(31954-27-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 31954-27-5(Hazardous Substances Data)

Usage

Description

BOC-GLY-OME, also known as N-[(1,1-Dimethyle thoxy)carbonyl]glycine Methyl Ester, is a derivative of the amino acid glycine. It is a colorless to yellow liquid and is widely used in various synthetic preparations of pharmaceutical goods and antioxidants.

Uses

Used in Pharmaceutical Industry:
BOC-GLY-OME is used as an intermediate in the preparation of Pregabalin, a GABA analogue used as an anticonvulsant.
Used in Chemical Industry:
BOC-GLY-OME is used as a chemical intermediate in various synthetic preparations.
Used in Paint and Dye Industry:
BOC-GLY-OME is used as an intermediate in the production of paint and dye products.
Used in Antioxidant Preparations:
BOC-GLY-OME is used in the synthesis of antioxidants for various applications.

InChI:InChI=1/C8H15NO4/c1-8(2,3)13-7(11)9-5-6(10)12-4/h5H2,1-4H3,(H,9,11)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 4530-20-5 BOC-glycine 
• 77-78-1 dimethyl sulfate 
• 77-76-9 2,2-dimethoxy-propane 
• 100-36-7 N,N-diethylethylenediamine 
• 395647-17-3 N-{3-[(N,N-dimethylaminophenyl)-4'-diazenyl]benzoyl}-N-tert-butyloxycarbonylglycine methyl ester 
• 1212-53-9 methyl N-benzyloxycarbonylglycinate 
• 57218-61-8 allyl methyl malonate 
• 75-65-0 tert-butyl alcohol 
• 186581-53-3 diazomethane 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 
• 616-34-2 methoxycarbonylmethylamine 

Downstream Products

• 61172-71-2 2-(tert-butoxycarbonylamino)-3-methoxy-3-oxopropanoic acid 
• 112392-58-2 dimethyl 2-oxo-3-(N-tert-butoxycarbonylamino)propane phosphonate 
• 26690-80-2 2-(N-tert-butoxycarbonylamino)ethanol 
• 89711-08-0 N-(t-butoxycarbonyl)glycinal 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 42492-57-9 methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate 
• 138219-39-3 2-bromo-2-(N-tert-butoxycarbonylamino)acetic acid methyl ester 
• 6926-09-6 (tert-butoxycarbonyl)glycine hydrazide 
• 223906-31-8 tert-butyl (2-hydroxy-2,2-diphenylethyl)carbamate 
• 183059-24-7 tert-butyl (2-hydroxy-2-methylpropyl)carbamate 
• 114703-81-0 (2-morpholin-4-yl-2-oxo-ethyl)-carbamic acid tert-butyl ester 
• 51987-73-6 methyl 2-tert-butoxycarbonylamino-3-phenylpropanoate 
• 341969-57-1 4-benzylamino-2,5-dihydro-pyrrole-1,3-dicarboxylic acid di-tert-butyl ester 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 

Relevant articles and documents

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