42303-42-4

Basic information

• Product Name: H-ACPC-OET HCL
• Synonyms: Ethyl 1-aminocyclopropane-1-carboxylate hydrochloride;H-AC3C-OEt Hydrochloride;H-ACPC-OET hydrochloride;methyl 1-aminocyclopropanecarboxylate, HCl salt;Ethyl 1-aminocyclopropanecarboxylate hydrochloride≥ 99% (Assay);1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID ETHYL ESTER HCL;ethyle1-aminocyclopropanecarboxylate hydrochloride;1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE
• CAS NO: 42303-42-4
• Molecular Formula: C₆H₁₂NO₂*Cl
• Molecular Weight: 165.62
• Product Categories: Amino Acid Derivatives
• Mol File: 42303-42-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: gt. 110.0 and le 118.0 °C
• Boiling Point: 159.7 °C at 760 mmHg
• Flash Point: 33.9 °C
• Appearance: White/Crystalline Powder
• Vapor Pressure: 2.47mmHg at 25°C
• Storage Temp.: Store at 0°C
• Water Solubility: Soluble in water
• CAS DataBase Reference: H-ACPC-OET HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-ACPC-OET HCL(42303-42-4)
• EPA Substance Registry System: H-ACPC-OET HCL(42303-42-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-38-36/37-24/25-22-7/9-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 42303-42-4(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C6H11NO2.ClH/c1-2-9-5(8)6(7)3-4-6;/h2-4,7H2,1H3;1H

Upstream product

• 3697-66-3 1,1-cyclopropanedicarboxylic acid monoethyl ester 
• 1559-02-0 diethyl cyclopropane-1,1-dicarboxylate 
• 72784-47-5 ethyl 1-aminocyclopropane-1-carboxylate 
• 107259-05-2 1-tert-butoxycarbonylamino-cyclopropanecarboxylic Acid Ethyl Ester 
• 64-17-5 ethanol 
• 22059-21-8 aminocyclopropane-1-carboxylic acid 

Downstream Products

• 957122-42-8 ethyl 1-[(2-oxo-2-phenylethyl)amino]cyclopropanecarboxylate 
• 868408-85-9 6-(2-bromo-5-chloro-4-fluoro-phenyl)-4,6-diaza-spiro[2.4]heptane-5,7-dione 
• 107259-05-2 1-tert-butoxycarbonylamino-cyclopropanecarboxylic Acid Ethyl Ester 
• 1237005-61-6 ethyl 1-(benzoylamino)cyclopropanecarboxylic acid 
• 1346136-24-0 2-(trimethylsilyl)ethyl 3-{[1-(ethoxycarbonyl)cyclopropyl]sulfamoyl}benzoate 
• 1434503-87-3 1-(2-(((1-isopentyl-1H-benzo[d]imidazol-2-yl)methyl)amino)benzamido)cyclopropanecarboxylic acid 

Relevant articles and documents

Gold-Catalyzed Amide/Carbamate-Linked N, O-Acetal Formation with Bulky Amides and Alcohols

A gold-catalyzed N,O-acetal formation was established to construct an amide/carbamate-linked N,O-acetal substructure with bulky alcohols. The acyliminium cation species generated from o-alkynylbenzoic acid ester in the presence of a gold catalyst is highly reactive and underwent nucleophilic attack of various bulky alcohols and phenols at room temperature under neutral conditions, leading to the corresponding N,O-acetals in yields of 34-89% with good functional group tolerance.

NOVEL COMPOUNDS

The present invention relates to inhibitors of the Wnt signalling pathways of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative disorder, as a sole agent or in combination with other active ingredients.

NOVEL COMPOUNDS

The present invention relates to substituted N-(phenyl-heteroaryl)-3-acetylamino-benzamides and N- [3-(acetylamino)phenyl]-phenyl-heteroaryl-carboxamides of general formula(I) as described and defined herein,to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease.