51644-83-8

Basic information

• Product Name: Z-D-GLU(OTBU)-OH
• Synonyms: Cbz-D-glutamic acid-gamma t-butyl ester;Z-D-glutaMic acid-gaMMa-tert-butyl ester;N-Benzyloxycarbonyl-D-glutaMic-acid 5-tert-butyl ester, 98%;N-[(Phenylmethoxy)carbonyl]-D-glutamic acid 5-(1,1-dimethylethyl) ester;D-GlutaMic acid,N-[(phenylMethoxy)carbonyl]-, 5-(1,1-diMethylethyl) ester;Z-D-Glu-OtBu;Z-D-glutamic acid γ-tert-butyl ester99%;N-ALPHA-BENZYLOXYCARBONYL-D-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER
• CAS NO: 51644-83-8
• Molecular Formula: C₁₇H₂₃NO₆
• Molecular Weight: 337.37
• Product Categories: Z-Amino Acids and Derivatives;Z-Amino acid series
• Mol File: 51644-83-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 522.6 °C at 760 mmHg
• Flash Point: 269.9 °C
• Appearance: /Solid
• Density: 1.197 g/cm³
• Vapor Pressure: 9.49E-12mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: 2-8°C
• PKA: 3.80±0.10(Predicted)
• CAS DataBase Reference: Z-D-GLU(OTBU)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-GLU(OTBU)-OH(51644-83-8)
• EPA Substance Registry System: Z-D-GLU(OTBU)-OH(51644-83-8)

Safety Data

• Hazardous Substances Data: 51644-83-8(Hazardous Substances Data)

Usage

General Description

Z-D-GLU(OTBU)-OH, also known as N-CBZ-L-glutamic acid alpha-tert-butyl ester, is a chemical compound used in organic synthesis and pharmaceutical research. It is a derivative of L-glutamic acid, an important amino acid commonly found in proteins. The OTBU group is a protecting group that helps to prevent unwanted reactions during the synthesis process. Z-D-GLU(OTBU)-OH is known for its ability to act as a chiral building block in the creation of complex molecules and can be used in the production of various pharmaceuticals and biologically active compounds. Its unique structure and properties make it a valuable tool for chemists and researchers working in the field of organic chemistry and drug development.

InChI:InChI=1/C17H23NO6/c1-17(2,3)24-14(19)10-9-13(15(20)21)18-16(22)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,20,21)/t13-/m1/s1

Upstream product

• 501-53-1 benzyl chloroformate 
• 45125-00-6 (R)-2-amino-5-(tert-butoxy)-5-oxopentanoic acid 

Downstream Products

• 63648-73-7 N-benzyloxycarbonyl-D-glutamic acid 
• 56877-41-9 N-(benzyloxycarbonyl)-D-glutamic acid 5-tert-butyl ester 1-methyl ester 
• 151301-90-5 1-dimethylethyl 5-[[4-(4-cyanophenyl)butyl]amino]-5-oxo-4(R)-[[(phenylmethoxy)carbonyl]amino]pentanoate 
• 106930-52-3 tert-butyl (4R)-4-{[(benzyloxy)carbonyl]amino}-5-hydroxypentanoate 
• 1273534-82-9 C₃₈H₅₅N₅O₉ 
• 200616-40-6 (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid 
• 1073843-73-8 4-(benzyloxycarbonylamino)-5-[2-benzoyl-5-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylamino]-5-oxopentanoic acid tert-butyl ester 
• 1073843-62-5 4-(benzyloxycarbonylamino)-5-[2-benzoyl-6-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenylamino]-5-oxopentanoic acid tert-butyl ester 
• 1025728-78-2 C₃₃H₄₅N₃O₇Si 
• 1025728-85-1 C₂₉H₃₅N₃O₇ 
• 140837-99-6 (2R)-N-benzyloxycarbonyl-N-methylglutamic acid α-methyl ester γ-t-butyl ester 
• 77277-62-4 N-(benzyloxycarbonyl)-L-valyl-D-isoglutamine t-butyl ester 
• 174488-24-5 tert-butyl (4R)-4-{N-{N-{4-[N-((6RS)-2-methyl-4-oxo-3,4,7,8-tetrahydro-6H-cyclopenta[g]quinazolin-6-yl)-N-(prop-2-ynyl)amino]benzoyl}-α-tert-butyl-L-γ-glutamyl}amino}-4-(5-tetrazolyl)butyrate 

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