70728-89-1

Basic information

• Product Name: 2-broMo-4,4'-di-tert-butylbiphenyl
• Synonyms: 2-broMo-4,4'-di-tert-butylbiphenyl;2-Bromo-4,4'-di-tert-butyl-1,1'-biphenyl
• CAS NO: 70728-89-1
• Molecular Formula: C₂₀H₂₅Br
• Molecular Weight: 345.3165
• Mol File: 70728-89-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 89.4-90.9 °C(Solv: ethanol (64-17-5))
• Boiling Point: 367.5±11.0 °C(Predicted)
• Appearance: /
• Density: 1.134±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-broMo-4,4'-di-tert-butylbiphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2-broMo-4,4'-di-tert-butylbiphenyl(70728-89-1)
• EPA Substance Registry System: 2-broMo-4,4'-di-tert-butylbiphenyl(70728-89-1)

Safety Data

• Hazardous Substances Data: 70728-89-1(Hazardous Substances Data)

Usage

General Description

2-bromo-4,4'-di-tert-butylbiphenyl is a chemical compound with the molecular formula C20H25Br. It is a derivative of biphenyl, a type of aromatic hydrocarbon. 2-broMo-4,4'-di-tert-butylbiphenyl is characterized by the presence of two bromine atoms and two tert-butyl groups attached to the biphenyl structure. It is commonly used in the field of organic chemistry as a building block for the synthesis of various organic compounds. Its distinctive molecular structure and properties make it an important intermediate for the production of pharmaceuticals, agrochemicals, and materials for electronic applications. Additionally, it has been studied for its potential biological activities and is of interest in medicinal chemistry research.

Upstream product

• 1625-91-8 4,4'-di-tert-butylbiphenyl 
• 70728-93-7 2,2′-dibromo-4,4′-di-tert-butylbiphenyl 

Downstream Products

• 409359-65-5 2-bromo-9-(4,4'-di-tert-butyl-biphenyl-2-yl)-9H-fluoren-9-ol 

Relevant articles and documents

Reactions of (Et2NCH2CH2NEt 2)·H2SiCl2 with selected diorganometallic reagents of magnesium and lithium

Addition of the THF-insoluble di-Grignard reagent from 2,2′-dibromo- 4,4′-tert-butylbiphenyl (1) to a solution of [(teeda)·H 2SiCl2] in CH2Cl2/THF produced 2,7-di-tert-butyl-9H-9-silafluorene (3) in isolated, recrystallized yields of 2O, when reacted with [(teeda)·H2SiCl2] in CH2Cl 2/Et2O, gave similar yields of 5,10-dihydro-2,5,8- trimethylphenazasiline (4). In the absence of CH2Cl2 the major product produced from 1 was the spirocycle 2,2′,7,7′-tetra- tert-butyl-9,9′-spirobi[9H-9-silafluorene] both in a solvent-free form (5′) and as an ethanol solvate (5), both of which were crystallographically characterized. The spirocycle 2,2′,5,5′,8, 8′-hexamethyl-5,10-dihydro-10,10-spirobiphenazasiline (6) was formed from the reaction of the dilithio reagent of 2 in the absence of CH 2Cl2.

NEW PRECURSORS TO SILAFLUORENES

Conversion of 2,2'-dibromo-4,4'-di-t-butylbiphenyl and o-bromo-o'-chlorobiphenyl to organometallic reagents suitable for reaction with Me2SiCl2 to produce silafluorene has been developed.