7530-31-6

Basic information

• Product Name: 2-Propenamide, N-(4-aminophenyl)-
• CAS NO: 7530-31-6
• Molecular Formula: C9H10N2O
• Molecular Weight: 162.191
• Mol File: 7530-31-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, N-(4-aminophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, N-(4-aminophenyl)-(7530-31-6)
• EPA Substance Registry System: 2-Propenamide, N-(4-aminophenyl)-(7530-31-6)

Safety Data

• Hazardous Substances Data: 7530-31-6(Hazardous Substances Data)

Usage

General Description

2-Propenamide, N-(4-aminophenyl)- is a chemical compound with the molecular formula C9H10N2O. It is an amide derivative with a phenyl substituent and an amino group. 2-Propenamide, N-(4-aminophenyl)- is commonly used in the production of various polymers and plastics, as well as in the synthesis of pharmaceuticals and agricultural chemicals. It is also used in the manufacturing of dyes and pigments, and as a precursor for other chemical reactions. Additionally, it has been studied for its potential applications in the fields of organic chemistry and materials science. Overall, 2-Propenamide, N-(4-aminophenyl)- is a versatile chemical with various industrial and research uses.

Upstream product

• 79-10-7 acrylic acid 
• 106-50-3 1,4-phenylenediamine 
• 100-01-6 4-nitro-aniline 
• 814-68-6 acryloyl chloride 
• 71026-66-9 N-(tert-butoxycarbonyl)-1,4-phenylenediamine 
• 7766-38-3 N-(4-nitrophenyl) acrylamide 
• 100-25-4 para-dinitrobenzene 
• 7439-89-6 iron 

Downstream Products

• 473430-67-0 N-{4-[4-(3,4,5-trimethoxy-phenylamino)-[1,3,5]triazin-2-ylamino]-phenyl}-acrylamide 
• 1357381-90-8 pyrrolidine-1-carboxylic acid (4-acryloylaminophenyl)-amide 
• 1374640-70-6 (N-(3-(2-(4-(4-acetylpiperazin-1-yl)-2-methoxyphenylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)phenyl)acrylamide) 

Relevant articles and documents

Discriminating detection of multiple analytes (F- and CN-) by a single probe through colorimetric and fluorescent dual channels

Abstract Two novel Schiff base type receptors containing phenol hydroxyl group (1) or methoxy group (2) were designed and synthesized. The receptor 1 with phenol hydroxyl group exhibited different colorimetric and fluorimetric responses to fluoride and cy

Design, synthesis and structure-activity relationship of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure as multi-target inhibitors against receptor tyrosine kinase

Inspired by that the multi-target inhibitors against receptor tyrosine kinases (RTKs) have significantly improved the effect of clinical treatment for cancer, and based on the chemical structure of Linifanib (ABT-869, Abbott), two series of diaryl-ureas with novel isoxazol[3,4-b]pyridine-3-amino-structure were designed and synthesized as multi-target inhibitors against RTKs. The preliminary biological evaluation showed that several compounds exhibited comparable potency with Linifanib. Compound S21 was identified as the most potent inhibitor against Fms-like tyrosine kinase 3 (FLT-3), kinase insert domain containing receptor (KDR) and platelet-derived growth factor receptor β (PDGFR-β) with its IC50 values were 4 nM, 3 nM and 8 nM respectively, it also showed potent inhibitory activities against several cancer cells.

A polymerizable monomer preparation method and application of

The invention provides a preparation method and application of a polymerizable monomer. The method comprises the following steps of: (1) under the condition of an amidation reaction, enabling aromatic diamine with the structure as shown in the formula (I) to be in contact with acrylic so as to obtain an intermediate M with the structure as shown in the formula (II); and (2)under the condition of a condensation reaction, enabling the intermediate M to be in contact with binary fatty acid with the structure as shown in the formula (III) so as to obtain the polymerizable monomer as shown in the formula (IV), wherein n is an integer of 0-5, and m is an integer of 1-10. The purity and the yield of products obtained by the method are high, and the production cost is low. The polymerizable monomer provided by the invention is enabled to be co-polymerized to other monomers, so that an oil-driving polymer with high molecular, high apparent viscosity, excellent heat resistance and excellent salt resistance can be obtained. An oil displacement agent compounded by the polymer and a surfactant has higher stickiness, excellent heat resistance and excellent salt resistance.

TANK-BINDING KINASE INHIBITOR COMPOUNDS

Compounds having the following formula (I) and methods of their use and preparation are disclosed: