99310-01-7 Usage
Description
N-Boc-N'-benzyloxymethyl-L-histidine, also known as BOC-D-HIS(3-BOM)-OH, is a chemical compound derived from L-histidine, an essential amino acid. It is characterized by the presence of a benzyloxy-methyl group and a Boc (tert-butyloxycarbonyl) protecting group, which are crucial for its reactivity and stability in various chemical reactions.
Uses
Used in Pharmaceutical Industry:
N-Boc-N'-benzyloxymethyl-L-histidine is used as a reactant for the synthesis of Land D-amino acid sequences in the preparation of snow flea antifreeze protein. This protein is of interest in the pharmaceutical industry due to its potential applications in the development of treatments for cryoprotectants, anti-freeze agents, and other therapeutic agents that require protection against freezing or cold-related injuries.
Additionally, the compound may be utilized in the synthesis of other bioactive peptides and proteins, given its unique structural features and reactivity. Its use in the pharmaceutical industry highlights the importance of innovative chemical compounds in drug discovery and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 99310-01-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,3,1 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 99310-01:
(7*9)+(6*9)+(5*3)+(4*1)+(3*0)+(2*0)+(1*1)=137
137 % 10 = 7
So 99310-01-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H25N3O5/c1-19(2,3)27-18(25)21-16(17(23)24)9-15-10-22(12-20-15)13-26-11-14-7-5-4-6-8-14/h4-8,10,12,16H,9,11,13H2,1-3H3,(H,21,25)(H,23,24)/t16-/m1/s1
99310-01-7Relevant articles and documents
1,2-hydroxy phosphonates and derivatives thereof
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, (2008/06/13)
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N-morpholino derivatives and their use as anti-hypertensive agents
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, (2008/06/13)
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Protection of Histidine Side-chains with ?-Benzyloxymethyl- or ?-Bromobenzyloxymethyl-groups
Brown, Tom,Jones, John H.
, p. 648 - 649 (2007/10/02)
N(α)-t-Butoxycarbonyl-N(?)-benzyloxymethyl-L-histidine (1) and N(α)-t-butoxycarbonyl-N(?)-4-bromobenzyloxymethyl-L-histidine (2) have been prepared and shown to be suitable derivatives for peptide synthesis with histidine; the synthetic intermediates had