Journal of Organic Chemistry p. 15315 - 15322 (2019)
Update date:2022-08-05
Topics:
Wang, Jie
Pang, Yu-Bo
Tao, Na
Zeng, Run-Sheng
Zhao, Yingsheng
Highly efficient alkylation of β-chloro ketones and their derivatives was achieved by means of domino dehydrochlorination/Mn-enabled radical-based alkyl-alkyl cross-coupling reaction. In situ-generated α,β-unsaturated ketones and their analogues were identified as the reaction intermediates. Known bioactive compounds, such as melperone and azaperone, could be easily prepared from β-chloropropiophenone in two steps.
View MoreShandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Chengdu D-Innovation Pharmaceutical Co., Ltd
Contact:86-28-85105536
Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
HANGZHOU FOREWIN PHARMA CO., LTD
Contact:+86-571-89053961
Address:hangzhou
Weifang Jahwa Chemical Co.,Ltd
Contact:0086-536-8897731,8897730
Address:No.5166 East Dongfeng Street,Weifang,Shandong,China
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.
Contact:86-716-8331612
Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Doi:10.1016/j.bmcl.2005.07.030
(2005)Doi:10.1039/j39670000377
(1967)Doi:10.1039/c7cc07740h
(2018)Doi:10.1016/j.bmc.2009.02.010
(2009)Doi:10.1039/a904730a
(1999)Doi:10.1080/00397911003797833
(2011)