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the reaction mixture and washed with ethanol and
dried in an oven at 80 C for 8 hr. The recycled catalyst
ꢀ
applied for the next run and exhibited a little loss of cata-
lytic activity (Figure 7), which is confirmed the use
of catalyst.
Co wasn't detected in the reaction solutions based
on ICP-AES evaluation via the hot filtration approach.
After the solid-free filtrates were subsequently stirred
continuously under optimized reaction conditions for
its substrates as mentioned above, the results of
1,4-dihydropyridine were significantly less than 5 percent
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this recycled catalyst after two runs (TEM picture
(Figure 8), and the XRD spectrum (Figure 9) was
accessed along with also the results revealed that the
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4 | CONCLUSIONS
In summary, we developed a robust and efficient recycla-
ble catalyst, CoFe2O4@SiO2-NH2-CoII to use in a four-
component one-pot procedure for syntheses of ten novels
functionalized pyridine derivatives under green solvent
conditions at reflux in good to excellent yields (60–96%).
The described protocol has various advantages, including
simple work-up, short reaction times, green solvent,
impressive yields, easy purification, atom efficiency, mak-
ings the procedure attractive. We believe this method will
open broader catalytic applications in the fields of
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ACKNOWLEDGEMENTS
The authors are grateful to the University of Birjand for
financial support.
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CONFLICT OF INTEREST
There are no conflicts to declare.
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ORCID
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