Bulletin of the Chemical Society of Japan p. 2401 - 2404 (1988)
Update date:2022-08-12
Topics:
Naora, Hirokazu
Ohnuki, Takashi
Nakamura, Asao
A useful prostanoid synthon, 7-(2-hydroxy-5-oxo-1-cyclopentenyl)heptanoic acid (3), was prepared from commercially available cyclooctanone in two steps.Nine other related cyclopentanoids which are also valuable synthons for prostaglandins were obtained from 3 in reasonable yields via several steps.The procedure is capable of generating these synthons on a laboratory scale.
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