Bioorganic and Medicinal Chemistry Letters p. 3117 - 3120 (1998)
Update date:2022-08-29
Topics:
Graziani, Edmund I.
Cane, David E.
Betlach, Melanie C.
Kealey, James T.
McDaniel, Robert
The final step in the biosynthesis of methymycin, neomethymycin, and picromycin is an hydroxylation, shown to be carded out by the cytochrome P- 450 monooxygenase, PicK. Direct comparison of the relative k(cat)/K(m) values for the two substrates, YC-17 and narbomycin, showed a threefold rate preference of pick for narbomycin.
View MoreGoldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd
Contact:(86) 519-88782201 88784080 88785278
Address:Henglin town, changzhou,Jiangsu
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.
Contact:+86-0150-58101658
Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China
Jiaxing Trustworthy Import And Export Co.,Ltd
Contact:+86-573-82030555
Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
NingBO Hong Xiang Biochem.Co.Ltd
website:http://www.hxbiochem.com
Contact:0574-66003444
Address:Ning Bo Bei Lun
Doi:10.1021/jacs.5b00998
(2015)Doi:10.1016/S0040-4039(00)96083-0
(1987)Doi:10.1002/1521-3773(20010105)40:1<169::AID-ANIE169>3.0.CO;2-T
(2001)Doi:10.1016/0022-328X(93)80044-C
(1993)Doi:10.1021/jacs.8b09613
(2018)Doi:10.1107/S0108270105028799
(2005)