Tenapanor hydrochloride

Base Information

• Chemical Name: Tenapanor hydrochloride
• CAS No.: 1234365-97-9
• Molecular Formula: C50H68Cl6N8O10S2
• Molecular Weight: 1218.0
• European Community (EC) Number: 810-634-7
• UNII: 50605O2ZNS
• DSSTox Substance ID: DTXSID701027856
• Wikidata: Q27260760
• NCI Thesaurus Code: C152556
• RXCUI: 2199673
• Pharos Ligand ID: WN291L92X1JP
• ChEMBL ID: CHEMBL3301627
• Mol file: 1234365-97-9.mol

Synonyms:AZD1722;RDX5791;tenapanor

Chemical Property of Tenapanor hydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 14
• Rotatable Bond Count: 29
• Exact Mass: 1216.260149
• Heavy Atom Count: 76
• Complexity: 1770

Purity/Quality:

98% min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1CC(C2=C(C1)C(=CC(=C2)Cl)Cl)C3=CC(=CC=C3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)C4=CC=CC(=C4)C5CN(CC6=C5C=C(C=C6Cl)Cl)C.Cl.Cl
• Isomeric SMILES: CN1C[C@H](C2=C(C1)C(=CC(=C2)Cl)Cl)C3=CC(=CC=C3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)C4=CC=CC(=C4)[C@@H]5CN(CC6=C5C=C(C=C6Cl)Cl)C.Cl.Cl
• Recent ClinicalTrials: A Study to Evaluate the Safety and Efficacy of RDX5791 for the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS-C)
• Recent EU Clinical Trials: An exploratory Phase 2, randomized, double-blind, placebo-controlled, parallel design study to evaluate the safety, tolerability, and pharmacodynamics of AZD1722 in CKD patients with type 2 diabetes mellitus and albuminuria