4-Bromo-2'-nitrobiphenyl

Base Information

• Chemical Name: 4-Bromo-2'-nitrobiphenyl
• CAS No.: 35450-34-1
• Molecular Formula: C12H8BrNO2
• Molecular Weight: 278.105
• Hs Code.: 2904909090
• Mol file: 35450-34-1.mol

Synonyms:2-nitro-4'-bromo-biphenyl;2-Nitro-4'-brom-biphenyl;1,1'-Biphenyl,4'-bromo-2-nitro;4'-Brom-2-nitro-biphenyl;4'-Bromo-2-nitrobiphenyl;

Chemical Property of 4-Bromo-2'-nitrobiphenyl

Chemical Property:

• Melting Point: 65-68℃
• Boiling Point: 372.39oC at 760 mmHg
• Flash Point: 179.015oC
• PSA: 45.82000
• Density: 1.522g/cm3
• LogP: 4.54750

Purity/Quality:

99% ^*data from raw suppliers

4′-Bromo-2-nitrobiphenyl Aldrich ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Bromo-2'-nitrobiphenyl

There total 16 articles about 4-Bromo-2'-nitrobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-nitrophenyl bromide (577-19-5) + 4-Bromophenylboronic acid (5467-74-3) → 4'-bromo-2-nitrobiphenyl (35450-34-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; at 90 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acschemneuro.8b00291

Reference yield: 94.0%

o-nitroiodobenzene (609-73-4) + 4-Bromophenylboronic acid (5467-74-3) → 4'-bromo-2-nitrobiphenyl (35450-34-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; for 12h; Inert atmosphere; Reflux;

Reference yield: 77.08%

2-nitrobiphenyl (86-00-0) → 4'-bromo-2-nitrobiphenyl (35450-34-1)

Guidance literature:

With iron(III) chloride; bromine; In tetrachloromethane; at 0 - 20 ℃; for 12h;

upstream raw materials:

2-nitrobiphenyl

4-bromo-1,1'-biphenyl

2'-nitro-biphenyl-4-ylamine

4-bromobenzenediazonium tetrafluoroborate

Downstream raw materials:

4-Bromobenzoic acid

9-(phenyl)-2-bromo-9H-carbazole

(9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid

2-(2-nitrophenyl)-9-phenyl-9H-carbazole

Refernces

• 1、 Antenucci, Achille,Barbero, Margherita,Dughera, Stefano,Ghigo, Giovanni. "Copper catalysed Gomberg-Bachmann-Hey reactions of arenediazonium tetrafluoroborates and heteroarenediazonium o-benzenedisulfonimides. Synthetic and mechanistic aspects". . . Retrieved 2020/10/20.
• 2、 -. "COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS". Paragraph 0290; 0291; 0292; 0306; 0310. . Retrieved 2018/12/11.