Narcobarbital

Base Information

• Chemical Name: Narcobarbital
• CAS No.: 125-55-3
• Deprecated CAS: 5992-36-9
• Molecular Formula: C₁₁H₁₅BrN₂O₃
• Molecular Weight: 303.156
• Hs Code.: 2933540000
• UNII: A77U8G9H84
• DSSTox Substance ID: DTXSID30871609
• Nikkaji Number: J5.376G
• Wikipedia: Narcobarbital
• Wikidata: Q906241
• Metabolomics Workbench ID: 154059
• ChEMBL ID: CHEMBL92963
• Mol file: 125-55-3.mol

Synonyms:5-(2-bromoallyl)-5-isopropyl-1-methylbarbituric acid;enibomal;enibomal sodium;eunarcon;narcobarbital;Narcodorm;pronarcon;pronarcon, (+-)-isomer;pronarcon, (R)-isomer;pronarcon, (S)-isomer;pronarcon, sodium salt

Chemical Property of Narcobarbital

Chemical Property:

• Melting Point: 115°
• Refractive Index: 1.519
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 66.48000
• Density: 1.405g/cm³
• LogP: 1.90240
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 302.02660
• Heavy Atom Count: 17
• Complexity: 406

Purity/Quality:

99%, ^*data from raw suppliers

Narcobarbital ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1(C(=O)NC(=O)N(C1=O)C)CC(=C)Br
• Uses: A Barbituric acid derivative

Technology Process of Narcobarbital

There total 3 articles about Narcobarbital which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(2-bromoallyl)-5-isopropylbarbituric acid (545-93-7) → Eunarcon (125-55-3)

Guidance literature:

With sodium hydroxide; dimethyl sulfate;

Reference yield:

2-bromoallyl bromide (513-31-5) → Eunarcon (125-55-3)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ Eunarcon (125-55-3)

Guidance literature:

4a, H2SO4;

DOI:10.1002/ardp.19763090303

upstream raw materials:

5-(2-bromoallyl)-5-isopropylbarbituric acid

2-bromoallyl bromide

Refernces