Chloromethyl chloroformate

Base Information Edit

Chemical Name:Chloromethyl chloroformate
CAS No.:22128-62-7
Molecular Formula:C2H2Cl2O2
Molecular Weight:128.943
Hs Code.:
European Community (EC) Number:244-793-3
UN Number:2745
DSSTox Substance ID:DTXSID9074567
Nikkaji Number:J26.283H
Wikipedia:Chloromethyl_chloroformate
Wikidata:Q5103099
Mol file:22128-62-7.mol

Synonyms:Chloromethyl chloroformate;22128-62-7;chloromethyl carbonochloridate;Chloroformic Acid Chloromethyl Ester;chloromethylchloroformate;Carbonochloridic acid, chloromethyl ester;EINECS 244-793-3;Chlorocarbonic acid chloromethyl ester;UN2745;Palite;Chlormethylchlorformiat;ClCO2CH2Cl;chloromethyl choroformate;choromethyl chloroformate;chloromethyl chlorocarbonate;1-chloromethyl chloroformate;SCHEMBL27366;DTXSID9074567;MFCD00077688;NA2745;AKOS005259776;chloroformic acid 1-chloromethyl ester;UN 2745;Formic acid, chloro-, chloromethyl ester;Chloromethyl chloroformate, >=98.0% (GC);EN300-86313;H11933;Chloromethyl chloroformate [UN2745] [Poison];J-014539;Q5103099

Suppliers and Price of Chloromethyl chloroformate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ChloroformicAcidChloromethylEster
50 g
$ 275.00

TCI Chemical
Chloromethyl Chloroformate >95.0%(GC)(T)
100g
$ 438.00

TCI Chemical
Chloromethyl Chloroformate >95.0%(GC)(T)
25g
$ 167.00

Sigma-Aldrich
Chloromethyl chloroformate ≥98.0% (GC)
10 mL
$ 163.00

Sigma-Aldrich
Chloromethyl chloroformate ≥98.0% (GC)
50 mL
$ 587.00

Medical Isotopes, Inc.
ChloroformicAcidChloromethylEster
1 g
$ 620.00

Alfa Aesar
Chloromethyl chloroformate 97%
50g
$ 277.00

Alfa Aesar
Chloromethyl chloroformate 97%
10g
$ 76.10

AHH
Chloromethyl chloroformate 98%
500g
$ 636.00

Total 1 raw suppliers

Chemical Property of Chloromethyl chloroformate Edit

Chemical Property:

Appearance/Colour:Colorless liquid
Vapor Pressure:26.5mmHg at 25°C
Melting Point:<-20 °C
Refractive Index:n20/D 1.428
Boiling Point:107.9 °C at 760 mmHg
Flash Point:25.5 °C
PSA：26.30000
Density:1.468 g/cm³
LogP:1.55810
Storage Temp.:2-8°C
Sensitive.:Moisture Sensitive
Water Solubility.:Slightly miscible with water.
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:127.9431847
Heavy Atom Count:6
Complexity:53.5
Transport DOT Label:Poison Corrosive

Purity/Quality:

97% ^*data from raw suppliers

ChloroformicAcidChloromethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 23-34
Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C(OC(=O)Cl)Cl
Uses Chloromethyl chloroformate is used as a reagent in the synthesis of carbamates and carbonates. Chloromethyl chloroformate is used as an intermediate in pharmaceuticals and in manufacture other chemicals. It acts as a reactant in the synthesis of aminocarbonyloxymethyl esters of diclofenac, flufenamic acid and in monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A.

Technology Process of Chloromethyl chloroformate

There total 9 articles about Chloromethyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%