Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide

Base Information

• Chemical Name: Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide
• CAS No.: 26934-29-2
• Molecular Formula: C5H10 N S . I
• Molecular Weight: 243.112
• Hs Code.: 2934100090
• European Community (EC) Number: 248-116-2
• DSSTox Substance ID: DTXSID20885376
• Mol file: 26934-29-2.mol

Synonyms:26934-29-2;2,3-Dimethyl-2-thiazolinium iodide;2,3-DIMETHYLTHIAZOLINIUM IODIDE;Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide;EINECS 248-116-2;2-Thiazolinium, 2,3-dimethyl-, iodide;4,5-Dihydro-2,3-dimethylthiazolium iodide;Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide (1:1);2,3-dimethyl-4,5-dihydro-1,3-thiazol-3-ium iodide;C5H10NS.I;DTXSID20885376;C5-H10-N-S.I;LS-151934;FT-0617178;2,3-dimethyl-4,5-dihydrothiazol-3-ium iodide;EN300-7355058;Thiazolium,4,5-dihydro-2,3-dimethyl-,iodide(1:1);3-(NAPHTHALENE-2-SULFONYL)-THIAZOLIDINE-2-CARBOXYLICACID

Chemical Property of Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 28.31000
• Density: g/cm³
• LogP: -2.24330
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 242.95787
• Heavy Atom Count: 8
• Complexity: 107

Purity/Quality:

99% ^*data from raw suppliers

2,3-DIMETHYLTHIAZOLINIUM IODIDE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=[N+](CCS1)C.[I-]

Technology Process of Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide

There total 2 articles about Thiazolium, 4,5-dihydro-2,3-dimethyl-, iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-methyl-4,5-dihydro-thiazole (2346-00-1) + methyl iodide (74-88-4) → 2,3-dimethylthiazolinium iodide (26934-29-2)

Guidance literature:

In acetonitrile; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/ejoc.200900514

Reference yield:

→ 2,3-dimethylthiazolinium iodide (26934-29-2)

Guidance literature:

Thiazolin 2I, Methyliodid;

Reference yield: 70.0%

2,3-dimethylthiazolinium iodide (26934-29-2) + 2-amino-benzenethiol (137-07-5) → 2-Methylbenzothiazole (120-75-2)

Guidance literature:

In N,N-dimethyl-formamide; for 2.5h; Heating;

DOI:10.1016/S0040-4020(01)87364-6

upstream raw materials:

2-methyl-4,5-dihydro-thiazole

methyl iodide

Downstream raw materials:

4-[2-(3-methyl-thiazolidin-2-yliden)-1-(4-oxo-3-phenyl-2-thioxo-thiazolidin-5-yliden)-ethyl]-biphenyl-3-carboxylic acid

5-methoxy-2-[2-(3-methyl-thiazolidin-2-yliden)-1-(4-oxo-3-phenyl-2-thioxo-thiazolidin-5-yliden)-ethyl]-benzoic acid

{5-[1-methyl-2-(3-methyl-thiazolidin-2-yliden)-ethyliden]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid

1-cyclohexyl-2-(3-methyl-thiazolidin-2-ylidene)-ethanone

Refernces

• 1、 Mercey, Guillaume,Lohier, Jean-Francois,Gaumont, Annie-Claude,Levillain, Jocelyne,Gulea, Mihaela. "Versatile synthesis of secondary 2-amino thiols and/or their disulfides via thiazolinium salts". supporting information; experimental part. p. 4357 - 4364. Retrieved 2011/02/24.
• 2、 Zhou, Aihua,Pittman, Charles U.. "Reactions of 2-methylthiazolines and N-methyl cyclic ketene-N,S-acetals with acid chlorides". . p. 8899 - 8903. Retrieved 2007/10/03.