Ethyl oxirane-2-carboxylate

Base Information

• Chemical Name: Ethyl oxirane-2-carboxylate
• CAS No.: 4660-80-4
• Molecular Formula: C5H8O3
• Molecular Weight: 116.117
• Hs Code.: 2918990090
• European Community (EC) Number: 225-105-0
• DSSTox Substance ID: DTXSID401317010
• Nikkaji Number: J297.875J
• Mol file: 4660-80-4.mol

Synonyms:ethyl glycidate;glycidic acid ethyl ester

Chemical Property of Ethyl oxirane-2-carboxylate

Chemical Property:

• Vapor Pressure: 0.043mmHg at 25°C
• Refractive Index: n20/D 1.4200(lit.)
• Boiling Point: 123.1 °C at 760 mmHg
• Flash Point: 38.3 °C
• PSA: 38.83000
• Density: 1.18 g/cm³
• LogP: -0.05170
• Storage Temp.: 2-8°C
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 116.047344113
• Heavy Atom Count: 8
• Complexity: 99.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl2,3-epoxypropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/38-43
• Safety Statements: 26

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=O)C1CO1

Technology Process of Ethyl oxirane-2-carboxylate

There total 14 articles about Ethyl oxirane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

dimethyl 8'-7',8'-dimethyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate (73245-18-8) → dimethyl 4,5-dimethylphthalate (17649-59-1) + ethyl glycidate (4660-80-4)

Guidance literature:

In ethanol; chloroform; at 12 - 20 ℃; for 1h;

DOI:10.1021/jo01299a030

Reference yield: 90.0%

dimethyl 1',8'-dimethyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate (73245-21-3) → dimethyl 3,5-dimethylphthalate (50919-64-7) + ethyl glycidate (4660-80-4)

Guidance literature:

In ethanol; chloroform; at 12 - 20 ℃; for 1h;

DOI:10.1021/jo01299a030

Reference yield: 88.0%

dimethyl 1'-methyl-8'-tert-butyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate (73245-23-5) → ethyl glycidate (4660-80-4) + dimethyl 5-(tert-butyl)-3-methylphthalate (73195-01-4)

Guidance literature:

In ethanol; chloroform; at 12 - 20 ℃; for 1h;

DOI:10.1021/jo01299a030

upstream raw materials:

ethyl acrylate

dimethyl 8'-7',8'-dimethyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate

dimethyl 1',8'-dimethyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate

dimethyl 1'-methyl-8'-tert-butyl-2'-oxospiro(oxirane-2,3'-bicyclo<2,2,2>octa<5,7>diene)-5',6'-dicarboxylate

Downstream raw materials:

C₁₆H₂₄O₄

C₃₇H₄₄O₁₀P₂

C₃₇H₄₄O₁₀P₂

ethyl 3-(((6-((trans)-4-tertbutylcyclohexyloxy)naphthalen-2-yl)methyl)amino)-2-hydroxypropanoate

Refernces

• 1、 Beharaj, Anjeza,Ekladious, Iriny,Grinstaff, Mark W.. "Poly(Alkyl Glycidate Carbonate)s as Degradable Pressure-Sensitive Adhesives". supporting information. p. 1407 - 1411. Retrieved 2019/01/14.
• 2、 -. "Α coccidiosis production of acrylic acid ester". Paragraph 0048; 0049. . Retrieved 2016/12/16.