N-(4-ethoxyphenyl)benzene-1,4-diamine

Base Information

• Chemical Name: N-(4-ethoxyphenyl)benzene-1,4-diamine
• CAS No.: 60457-49-0
• Molecular Formula: C14H16N2O
• Molecular Weight: 228.294
• Mol file: 60457-49-0.mol

Synonyms:

Chemical Property of N-(4-ethoxyphenyl)benzene-1,4-diamine

Chemical Property:

• Vapor Pressure: 1.34E-06mmHg at 25°C
• Boiling Point: 399.7°Cat760mmHg
• Flash Point: 195.6°C
• Density: 1.151g/cm³

Purity/Quality:

>95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-ethoxyphenyl)benzene-1,4-diamine

There total 11 articles about N-(4-ethoxyphenyl)benzene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + (4-ethoxy-phenyl)-phenyl-diazene (7466-38-8) → N-(4-ethoxy-phenyl)-p-phenylenediamine (60457-49-0) + 4-ethoxy-N2-phenyl-o-phenylenediamine (19950-91-5) + aniline (62-53-3) + 4-Ethoxyaniline (156-43-4)

Guidance literature:

Reference yield:

4-ethoxy-N-(4-nitrophenyl)aniline (1590-62-1) → N-(4-ethoxy-phenyl)-p-phenylenediamine (60457-49-0)

Guidance literature:

With ammonium chloride; zinc; at 80 ℃;

Reference yield:

4-Fluoronitrobenzene (350-46-9,178603-76-4) → N-(4-ethoxy-phenyl)-p-phenylenediamine (60457-49-0)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate / ethyl methyl ether / 7 h / Inert atmosphere; Reflux

2: potassium carbonate; potassium iodide / acetonitrile / Inert atmosphere; Reflux

3: tin(II)chloride dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere

With tin(II)chloride dihydrate; ethanol; sodium acetate; potassium carbonate; potassium iodide; In ethyl methyl ether; acetonitrile; 1: Ullmann reaction;

DOI:10.2174/157018012799859909

upstream raw materials:

4'-Nitroso-4-aethoxy-diphenylamin

4-ethoxy-N-(4-nitrophenyl)aniline

aniline

1-ethoxy-4-nitrobenzene

Downstream raw materials:

N,N'-bis-(4-phenetidino-phenyl)-thiourea

Refernces