N-FeruloyloctopaMine

Base Information

• Chemical Name: N-FeruloyloctopaMine
• CAS No.: 66648-44-0
• Molecular Formula: C18H19NO5
• Molecular Weight: 329.353
• Mol file: 66648-44-0.mol

Synonyms:N-trans-feruloy-3-O-methyldopamine;N-trans-feruloyl octopamine;N-trans-Feruloyloctopamin;trans-N-feruloyloctopamine;trans-N-feruloyl-3-O-methyldopamine;N-trans-Feruloylmethoxytyramine;N-trans-feruloyl 3-O-methyldopamine;

Chemical Property of N-FeruloyloctopaMine

Chemical Property:

• PSA: 99.02000
• LogP: 2.36030

Purity/Quality:

≥97% ^*data from raw suppliers

Octopamine, N-feruloyl- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-FeruloyloctopaMine

There total 3 articles about N-FeruloyloctopaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

octopamine (104-14-3,1915-83-9) + ferulic acid N-hydroxysuccinimidyl ester (56254-05-8) → (–)-trans-N-feruloyl octopamine (66648-44-0)

Guidance literature:

With sodium hydrogencarbonate; In water; acetone; for 24h;

DOI:10.1016/0031-9422(96)00173-2

Reference yield:

vanillin (121-33-5,8014-42-4) → (–)-trans-N-feruloyl octopamine (66648-44-0)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine; pyridine

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide

With piperidine; pyridine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;

DOI:10.1016/j.foodchem.2012.02.152

Reference yield:

octopamine (104-14-3,1915-83-9) + (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid (1135-24-6,537-98-4) → (–)-trans-N-feruloyl octopamine (66648-44-0)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;

DOI:10.1016/j.foodchem.2012.02.152

upstream raw materials:

octopamine

ferulic acid N-hydroxysuccinimidyl ester

(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

vanillin

Downstream raw materials:

triacetyl N-trans-feruloyl octopamine

Refernces

• 1、 Muehlenbeck, Ute,Kortenbusch, Albertus,Barz, Wolfgang. "Formation of hydroxycinnamoylamides and α-hydroxyacetovanillone in cell cultures of Solanum khasianum". . p. 1573 - 1579. Retrieved 2007/10/03.