dipyridin-4-ylmethanone(SALTDATA: FREE)

Base Information

• Chemical Name: dipyridin-4-ylmethanone(SALTDATA: FREE)
• CAS No.: 6918-15-6
• Molecular Formula: C11H8N2O
• Molecular Weight: 184.197
• Mol file: 6918-15-6.mol

Synonyms:

Chemical Property of dipyridin-4-ylmethanone(SALTDATA: FREE)

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 142°C
• Boiling Point: 346.4±17.0 °C(Predicted)
• PKA: 2.17±0.10(Predicted)
• Density: 1.196±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

dipyridin-4-ylmethanone ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dipyridin-4-ylmethanone may be used as a precursor to synthesize photoresponsive ligands such as diazodi(4-pyridyl)methane, which can be used in metal-carbene hetero-spin systems. This same product was previously listed as CBR00084.

Technology Process of dipyridin-4-ylmethanone(SALTDATA: FREE)

There total 6 articles about dipyridin-4-ylmethanone(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

4-pyridinecarboxylic acid, methyl ester (2459-09-8) + 4-bromopyridin (1120-87-2) → di-pyridin-4-yl-methanone (6918-15-6)

Guidance literature:

4-bromopyridin; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

4-pyridinecarboxylic acid, methyl ester; In tetrahydrofuran; diethyl ether; hexane; at -78 - -20 ℃; for 3.5h; Inert atmosphere;

DOI:10.1021/jacs.9b10414

Reference yield:

C11H8N2 → di-pyridin-4-yl-methanone (6918-15-6)

Guidance literature:

With air; In benzene; at 20 ℃; Kinetics; Irradiation;

DOI:10.1021/ol047467p

Reference yield:

4-bromopyridin (1120-87-2) → di-pyridin-4-yl-methanone (6918-15-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / -75 °C

2: diethyl ether

With diethyl ether;

upstream raw materials:

4-lithiopyridine

pyridine-4-carbonitrile

isonicotinic acid ethylester

4-bromopyridin

Downstream raw materials:

(2,4-dichloro-3-phenylquinolin-6-yl)(dipyridin-4-yl)methanol trifluoroacetate

2,6-di-tert-butyl-4-(di-pyridin-4-yl-methylene)-cyclohexa-2,5-dienone

γ,γ'-dipyridylmethane

3-[4-(4-Ethynyl-phenylethynyl)-phenyl]-1,1-di-pyridin-4-yl-prop-2-yn-1-ol

Refernces

• 1、 Minn et al.. "-". . p. 3600,3604,3606,3609. Retrieved 1970.
• 2、 -. "Substituted heterocyclylisoquinolinium salts and compositions and method of use thereof". . . Retrieved 2008/06/13.