Ethanone, 1-(3-nitrophenyl)-, O-methyloxime

Base Information

• Chemical Name: Ethanone, 1-(3-nitrophenyl)-, O-methyloxime
• CAS No.: 72278-09-2
• Molecular Formula: C9H10N2O3
• Molecular Weight: 194.19
• Mol file: 72278-09-2.mol

Synonyms:2.4-Dinitrophenylhydrazon des m-Nitro-acetophenons;-2.4-dinitrophenylhydrazon;m-Nitroacetophenone oxime methyl ether;3-Nitro-acetophenon-<2.4-dinitro-phenylhydrazon>;3'-nitroacetophenone 2,4-dinitrophenylhydrazone;

Chemical Property of Ethanone, 1-(3-nitrophenyl)-, O-methyloxime

Chemical Property:

• PSA: 67.41000
• LogP: 2.48840

Purity/Quality:

methoxy[1-(3-nitrophenyl)ethylidene]amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(3-nitrophenyl)-, O-methyloxime

There total 4 articles about Ethanone, 1-(3-nitrophenyl)-, O-methyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(E)-acetophenone O-methyloxime (15754-20-8) → (E)-1-(3-mitrophenyl)ethan-1-one O-methyl oxime (72278-09-2)

Guidance literature:

With dodecacarbonyl-triangulo-triruthenium; benzene; oxygen; silver nitrate; In 1,2-dichloro-ethane; at 100 ℃; for 30h; Reagent/catalyst; Temperature; Solvent; Mechanism; Catalytic behavior; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.7b01297

Reference yield: 21.0%

C13H12F3NO6Ru → (E)-1-(3-mitrophenyl)ethan-1-one O-methyl oxime (72278-09-2)

Guidance literature:

With benzene; oxygen; silver nitrate; In 1,2-dichloro-ethane; at 100 ℃; for 30h; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.7b01297

Reference yield:

m-nitroacetophenone oxime (7471-32-1) + methyl iodide (74-88-4) → (E)-1-(3-mitrophenyl)ethan-1-one O-methyl oxime (72278-09-2)

Guidance literature:

With methanol; potassium hydroxide; at 100 ℃;

upstream raw materials:

m-nitroacetophenone oxime

methyl iodide

3-Nitroacetophenone

(E)-acetophenone O-methyloxime

Downstream raw materials:

3-Nitroacetophenone

3-nitro-α-methylbenzylamine

(E)-1-(2,5-dinitrophenyl)ethanone O-methyl oxime

1-(1,1-difluoroethyl)-3-nitro-benzene

Refernces

• 1、 Fan, Zhoulong,Ni, Jiabin,Zhang, Ao. "Meta-Selective CAr-H Nitration of Arenes through a Ru3(CO)12-Catalyzed Ortho-Metalation Strategy". supporting information. p. 8470 - 8475. Retrieved 2016/07/26.