DL-2-AMINOBUTYRIC ACID

Base Information

• Chemical Name: DL-2-AMINOBUTYRIC ACID
• CAS No.: 80-60-4
• Molecular Formula: C₄H₉NO₂
• Molecular Weight: 103.121
• Mol file: 80-60-4.mol

Synonyms:DL-2-Amino-n-butyric acid;DL-alpha-Amino-n-butyric acid;alpha-Aminobutyric acid;Butyric acid, 2-amino-, DL- (8CI);

Chemical Property of DL-2-AMINOBUTYRIC ACID

Chemical Property:

• Melting Point: 291 °C (dec.)(lit.)
• Refractive Index: 1.4183 (estimate)
• Boiling Point: 215.166 °C at 760 mmHg
• PKA: 2.29(at 25℃)
• Flash Point: 83.93 °C
• PSA: 63.32000
• Density: 1.106 g/cm³
• LogP: 0.50860
• Water Solubility.: 167.40g/L(25 oC)

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-2-AMINOBUTYRIC ACID

There total 3 articles about DL-2-AMINOBUTYRIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.3%

N-acetyl-D-2-aminobutyric acid (7682-14-6) → D-α-amino-n-butyric acid (80-60-4,1492-24-6,2623-91-8,2835-81-6)

Guidance literature:

With hydrogenchloride; for 2.5h; Heating;

DOI:10.1246/bcsj.60.947

Reference yield:

2-aminobutanoic acid (2835-81-6) → L-α-amino-n-butyric acid (1492-24-6) + D-α-amino-n-butyric acid (80-60-4,1492-24-6,2623-91-8,2835-81-6)

Guidance literature:

DOI:10.1021/ja00535a059

Reference yield:

2-amino butyramide hydrochloride (89603-48-5,7682-20-4,141978-61-2) → L-2-amino-n-butanamide + D-α-amino-n-butyric acid (80-60-4,1492-24-6,2623-91-8,2835-81-6)

Guidance literature:

With sodium hydroxide; fungs treatment liquid; In water; at 40 ℃; for 22h; pH=7; Product distribution / selectivity; Enzymatic reaction;

upstream raw materials:

2-aminobutanoic acid

N-acetyl-D-2-aminobutyric acid

2-amino butyramide hydrochloride

Refernces

• 1、 Shiraiwa, Tadashi,Yoshida, Hirokazu,Tsuda, Makoto,Kurokawa, Hidemoto. "Racemic Structures of Organic Ammonium Salts of N-Acetyl-DL-2-aminobutyric Acid and N-Acetyl-DL-norvaline and Optical Resolution by Preferential Crystallization of DL-Ammonium Salts". . p. 947 - 952. Retrieved 2007/10/02.