1-(2,4-dinitrophenyl)piperidine

Base Information

• Chemical Name: 1-(2,4-dinitrophenyl)piperidine
• CAS No.: 839-93-0
• Molecular Formula: C11H13N3O4
• Molecular Weight: 251.242
• Hs Code.: 2933399090
• Mol file: 839-93-0.mol

Synonyms:Piperidine,4-dinitrophenyl);N-2,4-dinitrophenylpiperidine;1-piperidino-2,4-dinitrobenzene;1-(2,4-dinitro-phenyl)-piperidine;(2,4-dinitrophenyl)piperidine;1-(2,4-Dinitro-phenyl)-piperidin;

Chemical Property of 1-(2,4-dinitrophenyl)piperidine

Chemical Property:

• Vapor Pressure: 2.97E-07mmHg at 25°C
• Melting Point: 91-92.5 °C
• Boiling Point: 419.7°Cat760mmHg
• PKA: -0.52±0.40(Predicted)
• Flash Point: 207.6°C
• PSA: 94.88000
• Density: 1.355g/cm³
• LogP: 3.60470

Purity/Quality:

99% ^*data from raw suppliers

1-(2,4-DINITROPHENYL)PIPERIDINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2,4-dinitrophenyl)piperidine

There total 103 articles about 1-(2,4-dinitrophenyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

piperidine (110-89-4) + 2,4-Dinitrofluorobenzene (70-34-8,65727-75-5) → 1-(2,4-dinitrophenyl)piperidine (839-93-0)

Guidance literature:

With 2-hydroxypyridin; In benzene; at 25 ℃; Rate constant; other catalysts, other solvents, var. conc. of catalysts;

Reference yield: 99.0%

piperidine (110-89-4) + 1-chloro-2,4-dinitro-benzene (97-00-7) → 1-(2,4-dinitrophenyl)piperidine (839-93-0)

Guidance literature:

In acetonitrile; at 20 ℃; for 0.366667h;

DOI:10.1021/op2000699

Reference yield: 81.0%

N-phenyl piperidine (4096-20-2) → 1-(2,4-dinitrophenyl)piperidine (839-93-0)

Guidance literature:

With bismuth (III) nitrate pentahydrate; palladium diacetate; In 2,2,2-trifluoroethanol; trifluoroacetic acid; at 20 - 90 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2015.04.013

upstream raw materials:

piperidine

methanol

(2,4-dinitro-phenyl)-(4-nitro-phenyl)-ether

1-benzenesulfonyl-2,4-dinitro-benzene

Downstream raw materials:

N-methyl-2,4-dinitroaniline

piperidine

2,4-Dinitrophenol

5-nitro-2-(piperidin-1-yl)aniline

Refernces

• 1、 Correa, N. Mariano,Durantini, Edgardo N.,Silber, Juana J.. "Influence of Anionic and Cationic Reverse Micelles on Nucleophilic Aromatic Substitution Reaction between 1-Fluoro-2,4-dinitrobenzene and Piperidine". . p. 6427 - 6433. Retrieved 2000.
• 2、 Persson, Jonas,Axelsson, Svante,Matsson, Olle. "Solvent dependent leaving group fluorine kinetic isotope effect in a nucleophilic aromatic substitution reaction". . p. 20 - 23. Retrieved 1996.
• 3、 Correa, N. Mariano,Durantini, Edgardo N.,Silber, Juana J.. "Non-aqueous reverse micelles media for the SNAr reaction between 1-fluoro-2,4-dinitrobenzene and piperidine". . p. 805 - 812. Retrieved 2006.
• 4、 Gholami,Yangjeh, A. Habibi. "Dual-parameter correlations on rate of an aromatic nucleophilic substitution reaction in aqueous solutions of methanol, ethanol, and propan-2-ol". . p. 118 - 123. Retrieved 2001.
• 5、 Manne, Srinivasa Rao,Chandra, Jyoti,Mandal, Bhubaneswar. "Synthesis of o-Nitroarylamines via Ipso Nucleophilic Substitution of Sulfonic Acids". supporting information. p. 636 - 639. Retrieved 2019/01/21.