1,2,4-Trichloro-5-fluorobenzene

Base Information

• Chemical Name: 1,2,4-Trichloro-5-fluorobenzene
• CAS No.: 400-04-4
• Molecular Formula: C6H2 Cl3 F
• Molecular Weight: 199.439
• European Community (EC) Number: 206-921-6
• DSSTox Substance ID: DTXSID90193056
• Nikkaji Number: J213.643K
• Wikidata: Q83065773
• Mol file: 400-04-4.mol

Synonyms:1,2,4-Trichloro-5-fluorobenzene;400-04-4;2,4,5-Trichlorofluorobenzene;EINECS 206-921-6;C6H2Cl3F;C6-H2-Cl3-F;SCHEMBL7940907;DTXSID90193056;AC8775;MFCD00042116;Benzene, 1,2,4-trichloro-5-fluoro-;SY261629;1,2,4-tris(chloranyl)-5-fluoranyl-benzene;CS-0192386;EN300-7459558;A825803;Z1255431133

Chemical Property of 1,2,4-Trichloro-5-fluorobenzene

Chemical Property:

• Vapor Pressure: 0.27mmHg at 25°C
• Melting Point: 62 °C
• Boiling Point: 211.1°Cat760mmHg
• Flash Point: 86°C
• PSA: 0.00000
• Density: 1.54g/cm³
• LogP: 3.78590
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 197.920611
• Heavy Atom Count: 10
• Complexity: 120

Purity/Quality:

98%min ^*data from raw suppliers

1,2,4-Trichloro-5-fluorobenzene 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)F

Technology Process of 1,2,4-Trichloro-5-fluorobenzene

There total 10 articles about 1,2,4-Trichloro-5-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorobenzene (462-06-6) → 1,2,4-trichloro-5-fluoro-benzene (400-04-4)

Guidance literature:

With chlorine; iron; at 90 ℃;

Reference yield:

2-fluoro-4-chloro-1,3,5-trinitrobenzene (327-91-3) → 1,2,4-trichloro-5-fluoro-benzene (400-04-4)

Guidance literature:

With chlorine; at 200 ℃;

Reference yield:

2,4,5-trichloroaniline (636-30-6) → 1,2,4-trichloro-5-fluoro-benzene (400-04-4)

Guidance literature:

With hydrogenchloride; tetrafluoroboric acid; sodium nitrite; Erhitzen des Reaktionsprodukts auf 290grad;

upstream raw materials:

fluorobenzene

2-fluoro-4-chloro-1,3,5-trinitrobenzene

2,4,5-trichloroaniline

1-bromo-2,4-dichloro-5-fluorobenzene

Downstream raw materials:

undecachloro-fluoro-cyclohexane

2,3,4,5-Tetrachlorofluorobenzene

5-Fluor-2.3.6-trichlor-1-nitro-benzol

1-Fluor-3,6-dibrom-2,4,5-trifluorbenzol

Refernces