5-diazosalicylic acid

Base Information

• Chemical Name: 5-diazosalicylic acid
• CAS No.: 121-13-1
• Molecular Formula: C₇H₄N₂O₃
• Molecular Weight: 164.12
• Mol file: 121-13-1.mol

Synonyms:2-Carboxy-4-diazo-1-oxobenzene;3-Diazo-6-oxo-1,4-cyclohexadiene-1-carboxylic acid; 5-Diazosalicylic acid

Chemical Property of 5-diazosalicylic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 88.51000
• Density: g/cm³
• LogP: 0.24028

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-diazosalicylic acid

There total 2 articles about 5-diazosalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-Aminosalicylic Acid (89-57-6) → 5-Diazo-salicylsaeure (68596-89-4,121-13-1)

Guidance literature:

With pyridine hydrogenfluoride; sodium nitrite; 1.) O deg C, 20 min, 2.) 20 deg C, 1 h;

DOI:10.1016/0040-4020(95)00867-8

Reference yield:

→ 5-Diazo-salicylsaeure (68596-89-4,121-13-1)

Guidance literature:

5-Aminosalicylsaeure, NaNO2/70percentaq.HF;

Reference yield:

5-Diazo-salicylsaeure (68596-89-4,121-13-1) → 1,4-benzoquinone-2-carboxylic acid 4-O-oxide

Guidance literature:

Multi-step reaction with 2 steps

1: solid matrix / -263.2 °C / Irradiation

2: O₂ / solid matrix / -238.2 °C

With oxygen; In solid matrix;

upstream raw materials:

5-Aminosalicylic Acid

Downstream raw materials:

Triphenylphosphazid der Benzochinon-(1.4)-carbonsaeure

carbon dioxide

2,4-Didehydrophenol

3-Carboxy-4-oxo-2,5-cyclohexadienyliden

Refernces

• 1、 Fukuhara, Tsuyoshi,Yoneda, Norihiko,Takamura, Kouki,Suzuki, Akira. "The Preparation of p-Fluorophenols from p-Aminophenols: Diazotization and Fluorodiazoniation in Pyridine-HF.". . p. 299 - 304. Retrieved 2007/10/02.