Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)-

Base Information

• Chemical Name: Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)-
• CAS No.: 6155-50-6
• Molecular Formula: C₃₁H₄₆O₆
• Molecular Weight: 514.703
• Mol file: 6155-50-6.mol

Synonyms:Ruscogenin diacetate;Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)-;6155-50-6

Chemical Property of Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)-

Chemical Property:

• Vapor Pressure: 2.52E-13mmHg at 25°C
• Boiling Point: 577.3°Cat760mmHg
• Flash Point: 241.2°C
• Density: 1.16g/cm³
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 514.32943918
• Heavy Atom Count: 37
• Complexity: 990

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(C(CC(C6)OC(=O)C)OC(=O)C)C)C)C)OC1
• Isomeric SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5([C@@H](C[C@@H](C6)OC(=O)C)OC(=O)C)C)C)C)OC1

Technology Process of Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)-

There total 12 articles about Spirost-5-ene-1,3-diol, diacetate, (1beta,3beta,25R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

25(S)-ruscogenin 1-O-β-D-fucopyranosido-3-O-α-L-rhamnopyranoside (87425-34-1) → 25(S)-ruscogenin diacetate (6155-50-6,35319-88-1,66251-07-8,66251-10-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 N HCl-50 percent dioxane / 3 h / Heating

2: pyridine

With pyridine; hydrogenchloride;

Reference yield:

alliofuroside A (105798-62-7) → 25(S)-ruscogenin 1,3-diacetate (6155-50-6,35319-88-1,66251-07-8,66251-10-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 18 h / Heating

2: 4percent H₂SO₄ / H₂O / 8 h / 100 °C

3: 140 mg / pyridine / 30 h / Ambient temperature

With sulfuric acid; In pyridine; water;

DOI:10.1007/BF00574733

Reference yield:

alliospiroside A (39491-38-8,88668-51-3,105880-06-6,125225-63-0) → 25(S)-ruscogenin 1,3-diacetate (6155-50-6,35319-88-1,66251-07-8,66251-10-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 5percent HCl / methanol / 14 h / Heating

2: 140 mg / pyridine / 30 h / Ambient temperature

With hydrogenchloride; In pyridine; methanol;

DOI:10.1007/BF00574733

upstream raw materials:

acetic anhydride

(25R)-ruscogenin

25(S)-ruscogenin

25(S)-ruscogenin 1-O-α-L-rhamnopyranosyl-(1->2)-β-D-fucopyranoside

Refernces

• 1、 Watanabe, Yoshiaki,Sanada, Shuichi,Ida, Yoshiteru,Shoji, Junzo. "Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. I. Studies of the Constituents of the Subterranean Part of Liriope platyphylla Wang et Tang.". . p. 1980 - 1990. Retrieved 2007/10/02.