6-Methyl-DL-tryptophan

Base Information

• Chemical Name: 6-Methyl-DL-tryptophan
• CAS No.: 2280-85-5
• Molecular Formula: C12H14 N2 O2
• Molecular Weight: 218.255
• Hs Code.: 2933990090
• European Community (EC) Number: 218-916-6
• NSC Number: 1461
• DSSTox Substance ID: DTXSID801314256
• Nikkaji Number: J3.241.437K
• ChEMBL ID: CHEMBL538703
• Mol file: 2280-85-5.mol

Synonyms:6-Methyl-DL-tryptophan;2280-85-5;2-amino-3-(6-methyl-1H-indol-3-yl)propanoic acid;EINECS 218-916-6;6-Methyltryptophan #;SCHEMBL503549;CHEMBL538703;NSC1461;DTXSID801314256;NSC 1461;NSC-1461;6-Methyl-DL-tryptophan, crystalline;MFCD00022772;AKOS015962272;SB75303;CS-0201856;FT-0621232;A50543;A816367;2-Amino-3-(6-methyl-1H-indole-3-yl)propionic acid;2-azanyl-3-(6-methyl-1H-indol-3-yl)propanoic acid

Chemical Property of 6-Methyl-DL-tryptophan

Chemical Property:

• Melting Point: 290 °C (dec.)
• Boiling Point: 447.4°Cat760mmHg
• Flash Point: 224.4°C
• PSA: 79.11000
• Density: 1.313g/cm³
• LogP: 2.13100
• Storage Temp.: 2-8°C
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 218.105527694
• Heavy Atom Count: 16
• Complexity: 270

Purity/Quality:

99.5% ^*data from raw suppliers

6-Methyl-DL-tryptophan ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)C(=CN2)CC(C(=O)O)N

Technology Process of 6-Methyl-DL-tryptophan

There total 5 articles about 6-Methyl-DL-tryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[3-(6-methylindolyl)methyl]-4-hydroxy-2-hydroxyimino-glutalic acid ammonium salt (851364-80-2) → (2RS,4SR)-4-hydroxy-4-(6-methylindole-3-ylmethyl)glutamic acid + (2RS,4RS)-4-hydroxy-4-(6-methylindole-3-ylmethyl)glutamic acid + 6-methyl-DL-tryptophan (2280-85-5,1991-93-1,33468-34-7) + rac-Ala-OH (302-72-7,25191-17-7,18875-37-1)

Guidance literature:

With ammonia; hydrogen; 5% rhodium on carbon; In water; at 20 ℃; under 8360.56 Torr;

Reference yield:

→ 6-methyl-DL-tryptophan (2280-85-5,1991-93-1,33468-34-7)

Guidance literature:

With potassium hydroxide;

DOI:10.1039/jr9480000705 DOI:10.1021/ja01104a028

Reference yield:

→ 6-methyl-DL-tryptophan (2280-85-5,1991-93-1,33468-34-7)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01191a072

upstream raw materials:

4-[3-(6-methylindolyl)methyl]-4-hydroxy-2-hydroxyimino-glutalic acid ammonium salt

Downstream raw materials:

6-methyl-D-tryptophan

6-methyl-L-tryptophan

Refernces

• 1、 -. "Amino acid derivatives and sweetening agent". Page/Page column 8-9. . Retrieved 2010/02/11.