1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&

Base Information

• Chemical Name: 1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&
• CAS No.: 114932-60-4
• Molecular Formula: C24H19 N O4
• Molecular Weight: 385.419
• Mol file: 114932-60-4.mol

Synonyms:4-(1-Pyrene)butyric acid N-hydroxysuccinimide ester;2,5-Pyrrolidinedione,1-[1-oxo-4-(1-pyrenyl)butoxy]- (9CI);1-Pyrenebutanoic acid succinimidyl ester;1-Pyrenebutyric acid N-hydroxysuccinimide ester;4-(1-Pyrene)butanoic acidsuccimidyl ester;

Chemical Property of 1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&

Chemical Property:

• Appearance/Colour: Powder
• Vapor Pressure: 6.13E-14mmHg at 25°C
• Melting Point: 132-136 °C(lit.)
• Refractive Index: 1.738
• Boiling Point: 590.9°Cat760mmHg
• Flash Point: 311.2°C
• PSA: 63.68000
• Density: 1.37g/cm³
• LogP: 4.45180
• Storage Temp.: room temp
• Solubility.: Soluble in chloroform, N,N- dimethylformamide, dimethyl sulfoxide, methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-HydroxysuccinimidylPyrenebutanoate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: N-Hydroxysuccinimidyl Pyrenebutanoate is a novel fluorescent monomer used as new material for protein conjugation. N-Hydroxysuccinimidyl Pyrenebutanoate is a novel fluorescent monomer used as new material for protein conjugation. Dyes and metabolites.

Technology Process of 1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI&

There total 7 articles about 1-PYRENEBUTYRIC ACID N-HYDROXYSUCCINIMI& which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 1-pyrenebutyric acid (3443-45-6) → 4-(1-pyrene)butyric acid N-hydroxysuccinimide ester (114932-60-4)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 18h;

DOI:10.1002/cplu.201700512

Reference yield: 73.0%

1-pyrenebutyric acid (3443-45-6) + O-succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium tetrafluoroborate → 4-(1-pyrene)butyric acid N-hydroxysuccinimide ester (114932-60-4)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(02)00090-4

Reference yield:

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + 4-(pyren-1-yl)butyryl chloride (63549-37-1) → 4-(1-pyrene)butyric acid N-hydroxysuccinimide ester (114932-60-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2017.06.038

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

1-pyrenebutyric acid

O-(N-succinimidyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate

n-docosanoic acid

Downstream raw materials:

1-pyrenebutyric acid hydrazide

1-hydroxy-pyrrolidine-2,5-dione

6-benzyloxyhexanoic acid 2-[2-(4-pyren-1-ylbutyrylamino)ethoxy]ethyl ester

bis(2,3,5,6-tetrachlorophenyl)-{4-[2-(1-pyrenebutylcarboxy)aminoethyl]-2,3,5,6-tetrachlorophenyl}methane

Refernces

• 1、 Li, Fei,Zhang, Biaobiao,Li, Xiaona,Jiang, Yi,Chen, Lin,Li, Yanqing,Sun, Licheng. "Highly efficient oxidation of water by a molecular catalyst immobilized on carbon nanotubes". . p. 12276 - 12279. Retrieved 2011.
• 2、 Yan, Yehai,Cui, Jian,Zhao, Shuai,Zhang, Jinfang,Liu, Jiwen,Cheng, Junmei. "Interface molecular engineering of single-walled carbon nanotube/epoxy composites". . p. 1928 - 1936. Retrieved 2012.
• 3、 Liu, Kai,Zheng, Lifei,Liu, Qing,De Vries, Jan Willem,Gerasimov, Jennifer Y.,Herrmann, Andreas. "Nucleic acid chemistry in the organic phase: From functionalized oligonucleotides to dna side chain polymers". . p. 14255 - 14262. Retrieved 2014.
• 4、 Attatsi, Isaac Kwaku,Zhu, Weihua,Liang, Xu. "Surface molecular engineering of axial-exchanged Fe(III)Cl- and Mn(III)Cl-porphyrins towards enhanced electrocatalytic ORRs and OERs". . . Retrieved 2020.
• 5、 Sadlowski, Corinne,Balderston, Sarah,Sandhu, Mandeep,Hajian, Reza,Liu, Chao,Tran, Thanhtra P.,Conboy, Michael J.,Paredes, Jacobo,Murthy, Niren,Conboy, Irina M.,Aran, Kiana. "Graphene-based biosensor for on-chip detection of bio-orthogonally labeled proteins to identify the circulating biomarkers of aging during heterochronic parabiosis". . p. 3230 - 3238. Retrieved 2018.
• 6、 Urraca, Javier L.,Moreno-Bondi, Maria C.,Orellana, Guillermo,Sellergren, Boerje,Hall, Andrew J.. "Molecularly imprinted polymers as antibody mimics in automated on-line fluorescent competitive assays". . p. 4915 - 4923. Retrieved 2007.
• 7、 Ryu, Hyein,Baek, Ji Hye,Choi, Myung Gil,Lee, Jong Chan,Chang, Suk-Kyu. "Cu2+-selective turn-on fluorescence signaling based on metal-induced hydrolysis of pyrenecarbohydrazide". . p. 2927 - 2930. Retrieved 2017.