Tripropylphosphine oxide

Base Information

• Chemical Name: Tripropylphosphine oxide
• CAS No.: 1496-94-2
• Molecular Formula: C9H21 O P
• Molecular Weight: 176.239
• Hs Code.: 2931900090
• NSC Number: 222455
• UNII: SQ4XT573VM
• DSSTox Substance ID: DTXSID1061732
• Nikkaji Number: J265.456C
• Wikidata: Q81989627
• Mol file: 1496-94-2.mol

Synonyms:Tripropylphosphine oxide;1496-94-2;Tri-n-propylphosphine oxide;Phosphine oxide, tripropyl-;1-dipropylphosphorylpropane;1-(dipropylphosphoryl)propane;NSC 222455;SQ4XT573VM;OP(n-C3H7)3;NSC-222455;Phosphine oxide,tripropyl-;MFCD00013915;tripropyl-phosphine oxide;UNII-SQ4XT573VM;C9H21OP;SCHEMBL563253;DTXSID1061732;C9-H21-O-P;NSC222455;AKOS026676570;LS-106046;FT-0633606;F8880-5136

Chemical Property of Tripropylphosphine oxide

Chemical Property:

• Appearance/Colour: white xtl.
• Vapor Pressure: 0.003mmHg at 25°C
• Melting Point: 39ºC
• Boiling Point: 293.6 °C at 760 mmHg
• Flash Point: 131.3 °C
• PSA: 26.88000
• Density: 0.875 g/cm³
• LogP: 3.57950
• Sensitive.: moisture sensitive
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 176.133002287
• Heavy Atom Count: 11
• Complexity: 108

Purity/Quality:

98%min ^*data from raw suppliers

Tri-n-propylphosphine oxide, min. 98% ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCP(=O)(CCC)CCC

Technology Process of Tripropylphosphine oxide

There total 19 articles about Tripropylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.1%

propan-1-ol (71-23-8) + hexapropyldiphosphonium diperchlorate → tris-n-propylphosphine (2234-97-1) + tri-n-propylphosphine oxide (1496-94-2) + tetrapropylphosphonium perchlorate

Guidance literature:

With triethylamine; In acetonitrile;

Reference yield: 80.0%

hexapropyldiphosphonium diperchlorate → tris-n-propylphosphine (2234-97-1) + tri-n-propylphosphine oxide (1496-94-2)

Guidance literature:

With water; In acetonitrile;

Reference yield: 69.0%

propyl bromide (106-94-5) → tri-n-propylphosphine oxide (1496-94-2)

Guidance literature:

With phosphorus; potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In tetrahydrofuran; water; at 60 - 65 ℃; for 7h;

upstream raw materials:

phosphoric acid triphenyl ester

n-propylmagnesium bromide

triphenyl phosphite

diethyl ether

Downstream raw materials:

B(C₆F₅)3(C₃H₇)3PO

Refernces

• 1、 Zagumennov, V. A.,Sizova, N. A.. "Effect of electrolysis conditions on the process of anodic oxidation of tertiary phosphines in the presence of camphene". . p. 1368 - 1373,6. Retrieved 2020/09/16.
• 2、 Fukuzumi, Shunichi,Shimoosako, Kanji,Suenobu, Tomoyoshi,Watanabe, Yoshihito. "Mechanisms of hydrogen-, oxygen-, and electron-transfer reactions of cumylperoxyl radical". . p. 9074 - 9082. Retrieved 2007/10/03.