17-Methyl-17-hydroxyandrosta-1,4,6-trien-3-one

Base Information

• Chemical Name: 17-Methyl-17-hydroxyandrosta-1,4,6-trien-3-one
• CAS No.: 28816-02-6
• Molecular Formula: C₂₀H₂₆O₂
• Molecular Weight: 298.425
• Nikkaji Number: J2.357.508F
• Mol file: 28816-02-6.mol

Synonyms:17 alpha-methyl-17 beta-hydroxyandrosta-1,4,6-trien-3- one;17-methyl-17-hydroxyandrosta-1,4,6-trien-3-one

Chemical Property of 17-Methyl-17-hydroxyandrosta-1,4,6-trien-3-one

Chemical Property:

• Vapor Pressure: 4.08E-10mmHg at 25°C
• Boiling Point: 453.1°Cat760mmHg
• Flash Point: 193°C
• PSA: 37.30000
• Density: 1.14g/cm³
• LogP: 3.82130
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 298.193280068
• Heavy Atom Count: 22
• Complexity: 628

Purity/Quality:

98%Min ^*data from raw suppliers

17ALPHA-METHYL-1,4,6-ANDROSTATRIENE-17BETA-OL-3-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2(C)O)C=CC4=CC(=O)C=CC34C
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)C=CC4=CC(=O)C=C[C@]34C

Technology Process of 17-Methyl-17-hydroxyandrosta-1,4,6-trien-3-one

There total 4 articles about 17-Methyl-17-hydroxyandrosta-1,4,6-trien-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

metandienone (72-63-9) → 17β-Hydroxy-3-oxo-17α-methyl-Δ1,4,6-androstatrien (28816-02-6)

Guidance literature:

With titanium(IV) oxide; In water; acetonitrile; Reagent/catalyst; UV-irradiation;

DOI:10.1016/j.ejps.2014.08.009

Reference yield:

→ 17α-Methyl-1,4,6-androstatrien-17β-ol-3-on (28816-02-6)

Guidance literature:

3β,17β-Dihydroxy-17α-methylandrost-5-en, Dichlordicyano-benzochinon;

DOI:10.1039/j39710002566

Reference yield:

→ 17β-Hydroxy-3-oxo-17α-methyl-Δ1,4,6-androstatrien (28816-02-6)

Guidance literature:

17α-Methyl-androsten-(5)-diol-(3β,17β), 3 val. 2,3-Dichlor-5,6-dicyan-benzochinon, sd. Dioxan, 36h;

DOI:10.1039/j39680002568

upstream raw materials:

metandienone

Refernces