2,2-Bis[4-(4-maleimidophenoxy)phenyl]propane

Base Information

• Chemical Name: 2,2-Bis[4-(4-maleimidophenoxy)phenyl]propane
• CAS No.: 79922-55-7
• Deprecated CAS: 137422-53-8,1459737-83-7,160499-61-6,160903-46-8,1634670-50-0,178949-90-1,184874-64-4
• Molecular Formula: C₃₅H₂₆N₂O₆
• Molecular Weight: 570.601
• DSSTox Substance ID: DTXSID8074104
• Nikkaji Number: J632.668D
• Wikidata: Q82002617
• Mol file: 79922-55-7.mol

Synonyms:79922-55-7;2,2-bis[4-(4-maleimidophenoxy)phenyl]propane;2,2-bis(4-(4-maleimidephenoxy)phenyl)propane;1-[4-[4-[2-[4-[4-(2,5-dioxopyrrol-1-yl)phenoxy]phenyl]propan-2-yl]phenoxy]phenyl]pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1,1'-[(1-methylethylidene)bis(4,1-phenyleneoxy-4,1-phenylene)]bis-;1H-Pyrrole-2,5-dione, 1,1'-((1-methylethylidene)bis(4,1-phenyleneoxy-4,1-phenylene))bis-;DAPPI;SCHEMBL94891;DTXSID8074104;XAZPKEBWNIUCKF-UHFFFAOYSA-N;MFCD09908251;Bisphenol A Bis(4-maleimidophenyl Ether);BS-29504;B4807;F10202;2,2-bis(4-(4-maleimidophenoxy)-phenyl) propane;2,2-bis[4-(4-maleimido phenoxy)phenyl]propane;1-{4-[4-(2-{4-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenoxy]phenyl}propan-2-yl)phenoxy]phenyl}-2,5-dihydro-1H-pyrrole-2,5-dione

Chemical Property of 2,2-Bis[4-(4-maleimidophenoxy)phenyl]propane

Chemical Property:

• Vapor Pressure: 4.05E-21mmHg at 25°C
• Melting Point: 163.0 to 167.0 °C
• Boiling Point: 729.2°C at 760 mmHg
• PKA: -0.15±0.20(Predicted)
• Flash Point: 394.8°C
• PSA: 93.22000
• Density: 1.34g/cm³
• LogP: 6.58590
• Solubility.: soluble in Dimethylformamide
• XLogP3: 6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 570.17908655
• Heavy Atom Count: 43
• Complexity: 991

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,2-bis[4-(4-Maleimidophenoxy)phenyl]propane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(=O)C=CC3=O)C4=CC=C(C=C4)OC5=CC=C(C=C5)N6C(=O)C=CC6=O

Technology Process of 2,2-Bis[4-(4-maleimidophenoxy)phenyl]propane

There total 5 articles about 2,2-Bis[4-(4-maleimidophenoxy)phenyl]propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.8%

BAA (1190053-16-7) → 2,2'-bis-[4-(4-maleimidephenoxy)phenyl]propane (79922-55-7)

Guidance literature:

With toluene-4-sulfonic acid; hydroquinone; In N,N-dimethyl-formamide; toluene; at 114 - 122 ℃; for 6h; Temperature;

Reference yield:

BPA (80-05-7) → 2,2'-bis-[4-(4-maleimidephenoxy)phenyl]propane (79922-55-7)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate; N,N-dimethyl-formamide / 12 h / Reflux

2: palladium 10% on activated carbon; hydrazine / ethanol; water / 12.5 h / 85 °C / Reflux

3: acetone / 0.5 h / 20 °C

4: sodium acetate; acetic anhydride / acetone / 3 h / Reflux

With palladium 10% on activated carbon; sodium acetate; acetic anhydride; potassium carbonate; N,N-dimethyl-formamide; hydrazine; In ethanol; water; acetone;

DOI:10.1007/s10973-010-1020-5

Reference yield:

2,2-bis-{4-(4-aminophenoxy)phenyl}propane (13080-86-9,158066-25-2) → 2,2'-bis-[4-(4-maleimidephenoxy)phenyl]propane (79922-55-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 0.5 h / 20 °C

2: sodium acetate; acetic anhydride / acetone / 3 h / Reflux

With sodium acetate; acetic anhydride; In acetone;

DOI:10.1007/s10973-010-1020-5

upstream raw materials:

BPA

BAA

2,2-bis-{4-(4-aminophenoxy)phenyl}propane

2,2-bis[4-(4-nitrophenoxy)phenyl]propane

Refernces

• 1、 -. "Method for preparing 2,2'-bis[4-(4-maleimidophenoxy)phenyl]propane". Paragraph 0027; 0030; 0031. . Retrieved 2017/08/30.