METHYL TRIPHENYLMETHYL ETHER

Base Information

• Chemical Name: METHYL TRIPHENYLMETHYL ETHER
• CAS No.: 596-31-6
• Molecular Formula: C20H18 O
• Molecular Weight: 274.362
• Mol file: 596-31-6.mol

Synonyms:Ether, methyltrityl (6CI,7CI,8CI); Methoxytriphenylmethane; Methyl triphenylmethyl ether;Methyl trityl ether; NSC 64; Triphenylmethyl methyl ether; Trityl methyl ether

Chemical Property of METHYL TRIPHENYLMETHYL ETHER

Chemical Property:

• Vapor Pressure: 2.89E-05mmHg at 25°C
• Melting Point: 81-83oC
• Boiling Point: 367.4°C at 760 mmHg
• Flash Point: 191.6°C
• PSA: 9.23000
• Density: 1.073
• LogP: 4.62490
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl triphenylmethyl ether ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: A trityl-cysteine analog as inhibitor of human mitotic kinesin Methyl Triphenylmethyl Ether is a trityl-cysteine analog as inhibitor of human mitotic kinesin.

Technology Process of METHYL TRIPHENYLMETHYL ETHER

There total 117 articles about METHYL TRIPHENYLMETHYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

methanol (67-56-1) + N-[[2'-(1-triphenylmethyltetrazol-5yl)biphenyl-4-yl]methyl]-N-valeryl-L-valine methyl ester (781664-81-1) → methyl N-((2’-(1H-tetrazol-5-yl)-[1,1’-biphenyl]-4-yl)methyl)-N-pentanoyl-L-valinate (137863-17-3) + methoxytriphenylmethane (596-31-6)

Guidance literature:

With thionyl chloride; at 0 - 25 ℃; for 4.5h;

DOI:10.1002/ardp.201100377

Reference yield: 37.0%

bromo-triphenyl-methane (596-43-0) → triphenylmethyl alcohol (76-84-6) + triphenylmethane (519-73-3) + methoxytriphenylmethane (596-31-6) + 4-trityl-1-(diphenylmethyl)benzene (3416-63-5)

Guidance literature:

With sodium methylate; In various solvent(s); for 5h; Further byproducts given; Heating;

Reference yield: 26.0%

trityl chloride (76-83-5) → triphenylmethyl alcohol (76-84-6) + triphenylmethane (519-73-3) + methoxytriphenylmethane (596-31-6) + 4-trityl-1-(diphenylmethyl)benzene (3416-63-5)

Guidance literature:

With sodium methylate; nitrobenzene; In various solvent(s); for 8h; Further byproducts given; Heating;

upstream raw materials:

benzoic acid methyl ester

diethyl ether

methanol

triphenylmethyl alcohol

Downstream raw materials:

tetraphenylmethane

4-<(triphenylmethoxy)methyl>benzyl chloride

methanol

formaldehyd

Refernces

• 1、 Pangia, Thomas M.,Davies, Casey G.,Prendergast, Joshua R.,Gordon, Jesse B.,Siegler, Maxime A.,Jameson, Guy N. L.,Goldberg, David P.. "Observation of Radical Rebound in a Mononuclear Nonheme Iron Model Complex". . p. 4191 - 4194. Retrieved 2018.
• 2、 Pangia, Thomas M.,Yadav, Vishal,Gérard, Emilie F.,Lin, Yen-Ting,De Visser, Sam P.,Jameson, Guy N. L.,Goldberg, David P.. "Mechanistic Investigation of Oxygen Rebound in a Mononuclear Nonheme Iron Complex". supporting information. p. 9557 - 9561. Retrieved 2019/08/26.