2,2,6,6-Tetramethylpiperidin-4-one hydrochloride

Base Information

• Chemical Name: 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride
• CAS No.: 33973-59-0
• Molecular Formula: C9H17NO^.HCl
• Molecular Weight: 191.701
• Hs Code.: 2933399090
• European Community (EC) Number: 251-769-6
• DSSTox Substance ID: DTXSID9067803
• Mol file: 33973-59-0.mol

Synonyms:33973-59-0;2,2,6,6-Tetramethylpiperidin-4-one hydrochloride;Triacetonamine Hydrochloride;2,2,6,6-Tetramethyl-4-piperidone hydrochloride;4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride;2,2,6,6-Tetramethyl-4-piperidone, hydrochloride;2,2,6,6-Tetramethyl-4-piperidone HCl;Triacetonamine (hydrochloride);2,2,6,6-tetramethylpiperidin-4-one;hydrochloride;EINECS 251-769-6;2,2,6,6-Tetramethyl-4-piperidone (hydrochloride);4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride (1:1);TriacetonamineHydrochloride;C9H17NO.ClH;2,2,6,6-tetramethylpiperidin-4-one,hydrochloride;DTXSID9067803;MFCD00012768;AKOS015999069;DS-18523;FT-0639140;T1147;2,2,6,6-Tetramethyl-4-piperidonium chloride;2,2,6,6-Tetramethyl-4-piperidinone hydrochloride;A822028;2,2,6,6-Tetramethyl-4-oxopiperidine hydrochloride;4-Piperidone, 2,2,6,6-tetramethyl-, hydrochloride;J-019404;2,2,6,6-Tetramethyl-4-azacyclohexanone Hydrochloride;2,2,6,6-Tetramethyl-4-piperidone hydrochloride, 98%;2,2,6,6-tetramethylpiperidin-1-ium-4-one

Chemical Property of 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride

Chemical Property:

• Appearance/Colour: White powder.
• Vapor Pressure: 0.248mmHg at 25°C
• Melting Point: 198 °C (dec.)(lit.)
• Boiling Point: 205.6 °C at 760 mmHg
• Flash Point: 73.2 °C
• PSA: 29.10000
• Density: 0.882g/cm³
• LogP: 2.62690
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 191.1076919
• Heavy Atom Count: 12
• Complexity: 164

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,2,6,6-Tetramethylpiperidin-4-one hydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: CC1(CC(=O)CC(N1)(C)C)C.Cl
• Uses: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS).

Technology Process of 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride

There total 1 articles about 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

2,2,6,6-Tetramethyl-4-piperidone (826-36-8) → 2,2,6,6-tetramethylpiperidin-4-one hydrochloride (33973-59-0)

Guidance literature:

With hydrogenchloride; In isopropyl alcohol; at 60 ℃; for 0.666667h; Inert atmosphere;

Reference yield: 98.0%

2,2,6,6-tetramethylpiperidin-4-one hydrochloride (33973-59-0) → 4-oxo-2,2,6,6-tetramethylpiperidin-oxyl (45985-26-0,2896-70-0)

Guidance literature:

With sodium tungstate; dihydrogen peroxide; In water; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)92284-7

Reference yield: 76.0%

[(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) + 2,2,6,6-tetramethylpiperidin-4-one hydrochloride (33973-59-0) → 4-cyano-2,2,6,6-tetramethylpiperidine (67845-90-3)

Guidance literature:

With potassium tert-butylate; In 1,2-dimethoxyethane; tert-butyl alcohol; 1.) 0 deg C, 45 min; 2.) room temp., 1 h.;

DOI:10.1002/jhet.5570210240

upstream raw materials:

2,2,6,6-Tetramethyl-4-piperidone

Downstream raw materials:

4-cyano-2,2,6,6-tetramethylpiperidine

4-hydroxy-2,2,6,6-tetramethylpiperidine

2,2,6,6-tetramethyl-4-hydroxy-4-(1-hydroxy-1-methylethyl)piperidine

2,2,2',2',6,6,6'6'-octamethyl-4,4'-dihydroxy-4,4'-bipiperidyl

Refernces

• 1、 -. "PROCESSES FOR PREPARING PYRROLIDINE COMPOUNDS". Paragraph 0078; 0079; 0080; 0081. . Retrieved 2019/02/15.